Distribution of antibiotic resistance and the presence of vancomycin-resistance genes (vanA and vanB) in Enterobacteriaceae isolated from the Sea of Marmara, the Canakkale Strait and the Istanbul Strait, Turkey

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dc.authoridAY, Mustafa/0000-0002-1765-4858
dc.contributor.authorCardak, Mine
dc.contributor.authorAltug, Gulsen
dc.contributor.authorAy, Mustafa
dc.contributor.authorErol, Ozlem
dc.date.accessioned2025-01-27T20:35:02Z
dc.date.available2025-01-27T20:35:02Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWe investigated the frequency of antibiotic resistance of Enterobacteriaceae and the presence of vancomyc-in-resistance genes in samples taken from the Sea of Marmara, and the Istanbul and Canakkale Straits, Turkey. Different colony -forming bacteria were isolated and identified with the VITEK 2 Compact 30 system. The antibiotic resistance of the isolates was determined by the disc diffusion method. The isolates were tested against amoxicilin, ampicillin, aztreonam, ceftazidime, cefotaxime, cefuroxime, ofloxacin, vancomycin, tetracycline, kanamycin and gentamycin. The presence of vancomyctn-resistance genes (vanA and vanB) was also investigated. The level of Enterobucteriaceue species was higher in the Sea of Marmara than in the Istanbul Strait and the Canakkale Strait. Isolates showing resistance to the greatest number of antibiotics were identified from E. colt isolates. The resistance of the selected bacterial isolates were as follows: kanamycin (82%), vancomycin (78%) and ampicillin (60%). Some intermediately vancomycin-resistant Enterobacteriaceae isolates had the vanA gene. This study provides evidence of widespread bacterial resistance to clinically relevant antibiotics in marine environments. It also contributes to the knowledge on the distribution of antibiotic resistance among Enterobacteriaceae and indicates the importance of control measures in domestic water treatment.
dc.description.sponsorshipIstanbul University [BAP 588/1408200609]; Canakkale Onsekiz Mart University [BAP 226]
dc.description.sponsorshipThis work was supported by the Scientific Research Projects from Istanbul University and Canakkale Onsekiz Mart University (Project numbers BAP 588/1408200609 and BAP 226, respectively). The authors are grateful to Prof. Dr. Ali Ismen for his help in coordinating the surveys. We also thank Ass. Prof. Umur Onal for his valuable comments on the manuscript. We are also grateful to research assistants, Pelin S. Ciftci Turetken and Mukadder Arslan Ihsanoglu, for their assistance during sampling.
dc.identifier.doi10.1515/ohs-2016-0017
dc.identifier.endpage190
dc.identifier.issn1730-413X
dc.identifier.issn1897-3191
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84975883867
dc.identifier.scopusqualityQ3
dc.identifier.startpage182
dc.identifier.urihttps://doi.org/10.1515/ohs-2016-0017
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23549
dc.identifier.volume45
dc.identifier.wosWOS:000378088600004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWalter De Gruyter Gmbh
dc.relation.ispartofOceanological and Hydrobiological Studies
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectCanakkale Strait
dc.subjectIstanbul Strait
dc.subjectSea of Marmara
dc.subjectBeta-lactam Antibiotics
dc.subjectPCR
dc.subjectvanA
dc.subjectvanB
dc.titleDistribution of antibiotic resistance and the presence of vancomycin-resistance genes (vanA and vanB) in Enterobacteriaceae isolated from the Sea of Marmara, the Canakkale Strait and the Istanbul Strait, Turkey
dc.typeArticle

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