Bioactivity of two Turkish endemic Centaurea species, and their major constituents

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dc.contributor.authorShoeb, Mohammad
dc.contributor.authorMacManus, Stephen M.
dc.contributor.authorJaspars, Marcel
dc.contributor.authorKong-Thoo-Lin, Paul
dc.contributor.authorNahar, Lutfun
dc.contributor.authorCelik, Sezgin
dc.contributor.authorSarker, Satyajit D.
dc.date.accessioned2025-01-27T18:56:27Z
dc.date.available2025-01-27T18:56:27Z
dc.date.issued2007
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs, armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
dc.identifier.doi10.1590/S0102-695X2007000200003
dc.identifier.endpage159
dc.identifier.issn0102-695X
dc.identifier.issue2
dc.identifier.scopus2-s2.0-34347222213
dc.identifier.scopusqualityQ2
dc.identifier.startpage155
dc.identifier.urihttps://doi.org/10.1590/S0102-695X2007000200003
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12985
dc.identifier.volume17
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSociedade Brasileira de Farmacognosia
dc.relation.ispartofRevista Brasileira de Farmacognosia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectArctiin; Asteraceae; Brine shrimp lethality assay; Centaurea mucronifera; Centaurea urvillei subs. armata; Compositae; DPPH; Lignan; Matairesinoside; MTT
dc.titleBioactivity of two Turkish endemic Centaurea species, and their major constituents
dc.typeArticle

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