Bioactivity of two Turkish endemic Centaurea species, and their major constituents
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Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sociedade Brasileira de Farmacognosia
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs, armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
Açıklama
Anahtar Kelimeler
Arctiin; Asteraceae; Brine shrimp lethality assay; Centaurea mucronifera; Centaurea urvillei subs. armata; Compositae; DPPH; Lignan; Matairesinoside; MTT
Kaynak
Revista Brasileira de Farmacognosia
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
17
Sayı
2
