Investigation of the effects of oleuropein rich diet on rat enteric bacterial flora

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dc.authoridTekin, Murat/0000-0001-6841-3045
dc.authoridAltinisik, Hatice Betul/0000-0001-9273-0876
dc.contributor.authorKiraz, A.
dc.contributor.authorSimsek, T.
dc.contributor.authorTekin, S. Z.
dc.contributor.authorElmas, S.
dc.contributor.authorTekin, M.
dc.contributor.authorSahin, H.
dc.contributor.authorAltinisik, H. B.
dc.date.accessioned2025-01-27T20:57:54Z
dc.date.available2025-01-27T20:57:54Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractOBJECTIVES AND BACKGROUND: Oleuropein is a phenolic compound of olive leaves. Enteric bacterial flora is very important for human health and diet is a directly affecting factor of enteric bacterial flora composition. In this study, it was hypothesized that oleuropein could reduce total aerobic bacterial count in rat caecal flora. METHODS: Twenty adult, male, Wistar albino rats were randomly divided into two groups. Group C (n=10) was fed with standard rat chow and water for 30 days. Group 0 (n=10) received olive leaf extract 20 mg/kg/day by intragastric gavage in addition to standard rat chow and water for 30 days. One gram of caecal content was collected from each rat and then consecutive 10-fold serial dilutions were prepared with a final concentration of 10(-8). Then 0.1 ml of each dilution were spread onto the surfaces of Plate Count Agar and Violet Red Bile Glucose Agar to enumerate the aerobic enteric bacteria. RESULTS: Total aerobic bacterial counts of Group 0 were significantly lower than of Group C in all agar plates inoculated with ceacal samples for every dilution (p<0.05). CONCLUSION: Adding oleuropein to enteral feeding solutions of critically ill patients may be adventageous in the presence of clinical conditions predisposing to bacterial translocation by reducing enteric bacterial counts (Tab. 1, Ref. 32). Text in PDF www.elis.sk.
dc.identifier.doi10.4149/BLL_2016_141
dc.identifier.endpage737
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue12
dc.identifier.pmid28127972
dc.identifier.scopus2-s2.0-85014990360
dc.identifier.scopusqualityQ2
dc.identifier.startpage734
dc.identifier.urihttps://doi.org/10.4149/BLL_2016_141
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26542
dc.identifier.volume117
dc.identifier.wosWOS:000392564800010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherComenius Univ
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listy
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectenteric bacteria
dc.subjectintensive care
dc.subjectoleuropein
dc.subjectrat
dc.titleInvestigation of the effects of oleuropein rich diet on rat enteric bacterial flora
dc.typeArticle

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