Frontal QRS-T Angle as a Prognostic Marker of Long-Term Mortality in Hemodialysis Patients

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dc.contributor.authorKaya, Caglar
dc.contributor.authorEbik, Mustafa
dc.contributor.authorOzturk, Cihan
dc.contributor.authorCakir, Merve Akbulut
dc.contributor.authorCakir, Emirhan
dc.contributor.authorKilic, Ilhan
dc.date.accessioned2026-02-03T11:59:40Z
dc.date.available2026-02-03T11:59:40Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: The electrocardiogram is a crucial, cost-effective, and noninvasive tool for assessing the risk of cardiac morbidity and mortality. The frontal QRS-T angle is a marker of ventricular repolarization. This study investigated whether the frontal QRS-T angle could predict mortality in hemodialysis patients over a seven-year follow-up period. Method: The study included 110 patients undergoing regular hemodialysis. Frontal QRS-T angles greater than 90 degrees were classified as wide. Patients were categorized based on the width of the QRS-T angle and the presence or absence of mortality. Electrocardiogram (ECG) parameters measured included the QRS, T axis, TP/QT ratio, fragmented QRS, TPe/QTc ratio, and the frontal QRS-T angle, defined as the absolute difference between the frontal QRS and T axes. Results: A total of 37 patients (34%) had a wide frontal QRS-T angle. The mean age was significantly higher in both the wide frontal QRS-T angle group and the deceased group. Ejection fraction was lower and the frontal QRS-T angle was wider in the mortality group (94 [31-113] vs. 33 [16-80], P < 0.001). In univariate and multivariate logistic regression analyses, having a wide QRS-T angle was associated with increased mortality (odds ratio [OR]: 8.08, confidence interval [CI]: 2.75-23.74, P < 0.001). Additionally, the presence of fragmented QRS also increased mortality risk (OR: 11.25, CI: 2.98-42.49, P < 0.001). Conclusion: Our findings demonstrate the independent prognostic value of the frontal QRS-T angle in patients undergoing hemodialysis, irrespective of ejection fraction status. This suggests that it may serve as a valuable tool in routine cardiovascular risk assessments, contributing to improved management strategies for this high-risk population.
dc.identifier.doi10.5543/tkda.2025.98252
dc.identifier.endpage517
dc.identifier.issn1016-5169
dc.identifier.issn1308-4488
dc.identifier.issue7
dc.identifier.scopus2-s2.0-105022314781
dc.identifier.scopusqualityQ4
dc.identifier.startpage510
dc.identifier.urihttps://doi.org/10.5543/tkda.2025.98252
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34366
dc.identifier.volume53
dc.identifier.wosWOS:001591392300006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260130
dc.subjectFrontal QRS-T angle
dc.subjecthemodialysis
dc.subjectlong-term mortality
dc.titleFrontal QRS-T Angle as a Prognostic Marker of Long-Term Mortality in Hemodialysis Patients
dc.typeArticle

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