Non-invasive assessment of corneal and conjunctival deterioration in soft contact lens users using anterior segment optical coherence tomography

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dc.contributor.authorErsan, Ismail
dc.contributor.authorArikan, Sedat
dc.contributor.authorKara, Selcuk
dc.contributor.authorGencer, Baran
dc.contributor.authorKoklu, Asiye
dc.contributor.authorTufan, Hasan Ali
dc.date.accessioned2025-01-27T20:43:40Z
dc.date.available2025-01-27T20:43:40Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground The aim was to evaluate the corneal and bulbar conjunctival thicknesses of soft contact lens (SCL) wearers using anterior segment optical coherence tomography (AS-OCT). Methods The epithelial and overall thicknesses of both the central cornea and the infero-temporal bulbar conjunctiva of SCL wearers (30 subjects) were obtained by Cirrus HD-OCT and compared with those of refraction-matched controls (30 subjects) and patients with emmetropia (30 subjects). Results The mean corneal epithelial thicknesses in SCL wearing, spectacle-wearing and emmetropic groups were 48.97 +/- 5.45, 52.18 +/- 4.84 and 53.18 +/- 5.05 mu m, respectively. The corneal epithelium of members of the SCL group was significantly thinner than in both the spectacles and emmetropic groups (p = 0.044 and 0.006, respectively), whereas the central corneal thickness did not differ between groups (p = 0.210). The mean conjunctival epithelial thicknesses in SCL, spectacles and emmetropic groups were 41.50 +/- 7.75, 54.33 +/- 8.39 and 49.10 +/- 7.11 mu m, respectively. Conjunctival epithelium in the SCL group was significantly thinner than in both spectacle-wearing and emmetropic groups (p < 0.001 and p = 0.001, respectively). The conjunctiva was significantly thinner in the SCL group compared to the spectacles group (p = 0.001) but not the emmetropic group. Conclusions Contact lens wear is related to thinning of both corneal and conjunctival layers. AS-OCT is a non-invasive and clinically applicable technique for assessing the involvement of the cornea and conjunctiva in contact lens wearers.
dc.identifier.doi10.1111/cxo.12363
dc.identifier.endpage567
dc.identifier.issn0816-4622
dc.identifier.issn1444-0938
dc.identifier.issue6
dc.identifier.pmid27029024
dc.identifier.scopus2-s2.0-84962592104
dc.identifier.scopusqualityQ2
dc.identifier.startpage564
dc.identifier.urihttps://doi.org/10.1111/cxo.12363
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24321
dc.identifier.volume99
dc.identifier.wosWOS:000640496600012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofClinical and Experimental Optometry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectanterior segment optical coherence tomography
dc.subjectconjunctiva
dc.subjectcornea
dc.subjectepithelial thickness
dc.subjectsoft contact lens
dc.titleNon-invasive assessment of corneal and conjunctival deterioration in soft contact lens users using anterior segment optical coherence tomography
dc.typeArticle

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