Delayed graft function in living-donor renal transplantation: a single-center experience with 1537 patients

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dc.contributor.authorOzkul, Faruk
dc.contributor.authorErbis, Halil
dc.contributor.authorYilmaz, Vural Taner
dc.contributor.authorOzturk, Bunyamin
dc.contributor.authorKocak, Huseyin
dc.contributor.authorOsmanoglu, Ibrahim Ali
dc.contributor.authorDinckan, Ayhan
dc.date.accessioned2025-01-27T20:41:11Z
dc.date.available2025-01-27T20:41:11Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: To analyze the incidence, clinical characteristics and possible causes of delayed graft function (DGF) among a large number of living kidney transplant recipients at a single center. Patients and Methods: We analyzed the medical records of 1537 patients over 18 years of age who received a kidney transplant from a living donor between January 2003 and June 2014. The demographic characteristics of the patients, graft survivals, acute rejection rates and renal functions were compared between patients with and without DGF. Results: Longer dialysis time before transplantation (50.6 +/- 53.1 vs. 31.4 +/- 42.9 months; P<0.001) and lower donor GFR (48.2 +/- 10.2 vs. 45.4 +/- 13 months; P=0.014) were associated with a greater incidence of DGF in this series. The DGF cases showed a higher incidence of acute rejection episodes (19.9% vs. 4.8%), chronic graft dysfunction (10% vs. 1%), prolonged hospitalization (16.8 +/- 6.7 days vs. 8.3 +/- 5.6 days), and worse renal function after 1-year follow-up period compared with non-DGF patients. Conclusions: Longer dialysis time before transplantation and lower donor GFR were associated with a higher risk for DGF, with prolonged hospitalization time, worse graft prognosis and higher rates of acute rejection episodes and chronic graft dysfunction.
dc.identifier.endpage6719
dc.identifier.issn1940-5901
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84964301466
dc.identifier.scopusqualityN/A
dc.identifier.startpage6716
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24056
dc.identifier.volume9
dc.identifier.wosWOS:000377959900172
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherE-Century Publishing Corp
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicine
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectDelayed graft function
dc.subjectliving donor
dc.subjectrenal transplantation
dc.titleDelayed graft function in living-donor renal transplantation: a single-center experience with 1537 patients
dc.typeArticle

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