Determination of Antimicrobial and Antioxidant Activity of Atropa belladonna L.

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dc.authorid0000-0001-5556-4880
dc.contributor.authorSayim, Merve Ulku
dc.contributor.authorPala, Ruveyde
dc.contributor.authorYaman, Cenker
dc.contributor.authorGul, Gizem
dc.contributor.authorBenek, Atakan
dc.contributor.authorTuru, Dilay
dc.contributor.authorBozyel, Mustafa Eray
dc.date.accessioned2026-02-03T12:00:21Z
dc.date.available2026-02-03T12:00:21Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim of study: Bacteria that have developed resistance to antibiotics have become one of the major challenges facing global healthcare systems. This study evaluates the antimicrobial and antioxidant effects of Atropa belladonna extracts against an extended variety of microbial strains, addressing the urgent need due to increasing resistance. Material and method: In this study, disc diffusion, minimum inhibitory concentration testing, and DPPH antioxidant analyses were conducted on the Atropa belladonna plant. Main results: Using the ethanol extract, antimicrobial activity was tested against 26 bacterial and one yeast strain by disc diffusion, showing inhibitory effects on six microorganisms (four standard strains and two food isolates). MIC assays identified activity against Bacillus subtilis DSMZ 1971, Candida albicans DSMZ 1386, and Enterococcus durans. The DPPH assay demonstrated the greatest antioxidant activity at 200 mg/mL concentration, reaching 71.34%. Research highlights: The study results emphasize the need to consider Atropa belladonna's antimicrobial and antioxidant capacities. Therefore, the study should be combined with various doses, strains, or methods.
dc.identifier.doi10.17475/kastorman.1787316
dc.identifier.endpage199
dc.identifier.issn1303-2399
dc.identifier.issn1309-4181
dc.identifier.issue2
dc.identifier.startpage188
dc.identifier.urihttps://doi.org/10.17475/kastorman.1787316
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34568
dc.identifier.volume25
dc.identifier.wosWOS:001588095200004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherKastamonu Univ
dc.relation.ispartofKastamonu University Journal of Forestry Faculty
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260130
dc.subjectAtropa belladonna L.
dc.subjectDisc diffusion Test
dc.subjectMinimum Inhibition Concentration
dc.subjectDPPH Test
dc.titleDetermination of Antimicrobial and Antioxidant Activity of Atropa belladonna L.
dc.typeArticle

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