Effect of luer-lock access device on hemolysis during blood collection via intravenous catheters in the emergency department

Basit Öğe Kaydı
dc.authorid0009-0003-3274-5605
dc.authorid0000-0002-7161-2907
dc.contributor.authorCinpolat, Havva Yasemin
dc.contributor.authorAkman, Canan
dc.contributor.authorSahin, Eda
dc.date.accessioned2026-02-03T12:00:23Z
dc.date.available2026-02-03T12:00:23Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives: Emergency departments are the units where hemolysis is most frequently observed, and blood collection from intravenous catheters increases the hemolysis rate. This study aimed to compare the effects of two different blood collection methods from an intravenous catheter (an adapter and a syringe) on serum indices, complete blood count, and routine clinical chemistry tests in an emergency department. Methods: The study encompassed 104 patients from the yellow and green zones of the Emergency Department at Canakkale Onsekiz Mart University Hospital. Blood samples were obtained from an intravenous catheter with a standard syringe and an adapter into serum separator tubes and dipotassium ethylenediaminetetraacetic acid (K(2)EDTA) tubes. Serum index, aspartate aminotransferase (AST), creatine kinase (CK), lactate dehydrogenase (LDH), potassium, high-sensitivity (hs) Troponin T, and complete blood count were evaluated. Passing-Bablok regression analysis was performed, and the mean percentage difference was calculated and compared to target values via a Bland-Altman plot. Results: A statistically higher hemolysis rate was observed when blood was collected with a syringe, compared to collecting blood with an adapter (p<0.001). When the results were categorized according to the parameter-specific hemolysis index, AST, CK, potassium, LDH, and hs Troponin T results were more affected by hemolysis when blood was collected with a syringe (p<0.001). The mean percentage difference for AST and LDH exceeded the minimum target values based on biological variation. Conclusions: Using a catheter-compatible adapter in emergency departments may reduce the rate of hemolysis and provide reliable results for tests frequently affected by hemolysis.
dc.description.sponsorshipdouble daggeranakkale Onsekiz Mart University Scientific Research Projects [THD-2023-4534]
dc.description.sponsorshipWe would like to thank Canakkale Onsekiz Mart University Hospital Medical Biochemistry Laboratory technicians and Emergency Service staff for their contributions during the conduct of this study.
dc.identifier.doi10.1515/tjb-2025-0027
dc.identifier.issn0250-4685
dc.identifier.issn1303-829X
dc.identifier.scopus2-s2.0-105021028491
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1515/tjb-2025-0027
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34590
dc.identifier.wosWOS:001608173700001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWalter De Gruyter Gmbh
dc.relation.ispartofTurkish Journal of Biochemistry-Turk Biyokimya Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260130
dc.subjectquality improvement
dc.subjectblood specimen collection
dc.subjectphlebotomy
dc.subjectspecimen handling
dc.subjectpreanalytical phase
dc.subjecthemolysis
dc.titleEffect of luer-lock access device on hemolysis during blood collection via intravenous catheters in the emergency department
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu