The Impact of Psychotropic Drugs on Psychosocial Functioning in Bipolar Disorder

Basit Öğe Kaydı
dc.authoridAydemir, Omer/0000-0003-3050-1263
dc.contributor.authorAydemir, Omer
dc.contributor.authorAydin, Pinar Cetinay
dc.contributor.authorOyeckin, Demet Gulec
dc.contributor.authorGulseren, Seref
dc.contributor.authorKoybasi, Gulperi Putgul
dc.contributor.authorSahin, Hasan
dc.date.accessioned2025-01-27T20:54:00Z
dc.date.available2025-01-27T20:54:00Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Even though bipolar patients achieve remission, they do not reach. premorbid psychosocial functioning. Factors such as residual depressive symptoms and number of episodes may cause this effect. The impact of treatment modalities has not been adequately studied. The aim of this study was to evaluate the impact of treatment modalities on psychosocial functioning in remitted bipolar patients. Methods: The study was carried out with 108 patients diagnosed as having bipolar disorder. All patients were in remission and the remission state was confirmed by rating scales. In the assessment of functioning, the Functioning Assessment Short Test (FAST) covering domains such as autonomy, occupational functioning, cognitive functioning, financial issues, interpersonal relations, and leisure time activities was applied. The treatment modalities were mood stabilizers (MS) versus mood stabilizers plus second-generation antipsychotics (MS+SGA). While 38% (n=41) of the patients were on MS only, 67 patients (62%) were on MS+SGA. In the statistical analysis, multiple linear regression analysis was performed. Results: In multiple linear regression analyses, the models concerning autonomy, interpersonal relations, and leisure time were statistically significant. In patients on MS+SGA, autonomy (Beta=3.086, p<0.01), interpersonal relations (Beta=2.807, p<0.01) and leisure time activities (Beta=3.293, p<0.01) were affected negatively. Similarly, total HAM-D score had negative effects on the same domains. Conclusion: Beside residual depressive symptoms, second-generation antipsychotics used in the treatment seem to affect psychosocial functioning negatively.
dc.identifier.doi10.5455/bcp.20140123034729
dc.identifier.endpage127
dc.identifier.issn1017-7833
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84904631799
dc.identifier.scopusqualityN/A
dc.identifier.startpage122
dc.identifier.urihttps://doi.org/10.5455/bcp.20140123034729
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25937
dc.identifier.volume24
dc.identifier.wosWOS:000339982500003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherKure Iletisim Grubu A S
dc.relation.ispartofKlinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectbipolar disorder
dc.subjectpsychosocial functioning
dc.subjectmood stabilizers
dc.subjectsecond-generation antipsychotics
dc.titleThe Impact of Psychotropic Drugs on Psychosocial Functioning in Bipolar Disorder
dc.title.alternativeİki uçlu bozuklukta kullani{dotless}lan ilaçlari{dotless}n psikososyal işlevsellik üzerine etkisi
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu