In vitro evaluation of antimicrobial features of vasopressors

Basit Öğe Kaydı
dc.authoridErdivanli, Basar/0000-0002-3955-8242
dc.authoridHanci, Volkan/0000-0002-2227-194X
dc.contributor.authorBostan, Habib
dc.contributor.authorTomak, Yakup
dc.contributor.authorKaraoglu, Sengul Alpay
dc.contributor.authorErdivanli, Basar
dc.contributor.authorHanci, Volkan
dc.date.accessioned2025-01-27T20:20:13Z
dc.date.available2025-01-27T20:20:13Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Drugs administered as intravenous infusion may be contaminated during several stages of production or preparation. However studies focusing on antibacterial effects of vasopressor drugs are very rare. This study investigates the in vitro antimicrobial activity of the clinically used forms of vasopressors. Materials and Methods: In vitro antimicrobial activities of vasopressor drugs of different concentrations were investigated by using the micro dilution technique. Microorganisms used in the test were Escherichia coli ATCC 25922, Yersinia pseudotuberculosis ATCC 911, Pseudomonas aeruginosa ATCC 10145, Listeria monocytogenes ATCC 43251, Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, Bacillus cereus 702 Roma, Mycobacterium smegmatis ATCC607, Candida albicans ATCC 60193, and Saccharomyces cerevisiae RSKK 251. Antibacterial assays were performed in Mueller-Hinton broth at pH 7.3 and antifungal assays were performed in buffered Yeast Nitrogen Base at pH 7.0. Results: Two different dopamine preparations showed antimicrobial activity. No other study drug showed any antimicrobial activity. Conclusions : In our opinion, dopamine's antibacterial effects may be advantageous for inhibiting the spread of bacterial contamination during the preparation of the infusion solutions. However, it is important that strict guidelines regarding the need for sterile equipment and deliverables be adhered to during all procedures performed in the intensive care units. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.
dc.identifier.doi10.1016/j.bjane.2013.02.002
dc.identifier.endpage88
dc.identifier.issn0034-7094
dc.identifier.issn1806-907X
dc.identifier.issue2
dc.identifier.pmid24794449
dc.identifier.scopus2-s2.0-84929510200
dc.identifier.scopusqualityN/A
dc.identifier.startpage84
dc.identifier.urihttps://doi.org/10.1016/j.bjane.2013.02.002
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21621
dc.identifier.volume64
dc.identifier.wosWOS:000337101400003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Inc
dc.relation.ispartofRevista Brasileira De Anestesiologia
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAntimicrobial
dc.subjectactivities
dc.subjectVasopressor drugs
dc.subjectDrug contamination
dc.titleIn vitro evaluation of antimicrobial features of vasopressors
dc.title.alternativeAvaliação in vitro das propriedades antimicrobianas de vasopressores
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu