Humic acid particle embedded super porous gum Arabic cryogel network for versatile use

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dc.authoridSağbaş Suner, Selin / 0000-0002-3524-0675
dc.authoridŞahiner, Nurettin / 0000-0003-0120-530X
dc.contributor.authorSağbaş Suner, Selin
dc.contributor.authorŞahiner, Nurettin
dc.date.accessioned2025-01-27T20:43:46Z
dc.date.available2025-01-27T20:43:46Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSuper porous gum Arabic (GA) cryogels were synthesized by crosslinking of natural GA with divinyl sulfone at cryogenic conditions, -20 degrees C for potential biomedical applications. Humic acid (HA) nanoparticles were also prepared by using degradable and biocompatible crosslinkers such as trimethylolpropane triglycidyl ether, poly(ethylene glycol) diglycidyl ether, and trisodium trimetaphosphate in a single step and then entrapped within GA cryogel network as GA/HA particle cryogel. Furthermore, GA/HA cryogel was used as a template for Ag, Cu, and Fe nanoparticle preparation, and their antimicrobial properties were tested against Escherichia coli, Staphylococcus aureus, and Bacillus subtilis strains. The minimum inhibition concentration values of Ag and Cu nanoparticle-loaded GA/HA cryogel composites were determined as 10mgmL(-1). Furthermore, the blood compatibility tests such as hemolysis and blood clotting indexes were determined for GA cryogels and found to be more compatible with 0.08 +/- 0.01% hemolysis and 89.4 +/- 6.1 blood clotting values, whereas the hemolysis of the Ag, Cu, and Fe nanoparticle-loaded GA/HA Ag, Cu, and Fe metal nanoparticle cryogel composites decreased in the order of Fe>Cu>Ag nanoparticles.
dc.description.sponsorshipCanakkale Onsekiz Mart University [COMU BAP, FDK-2017-1069]; TUBA [GEBIP-2008]; Scientific Research Commission of Canakkale Onsekiz Mart University [COMU BAP, FDK-2017-1069]
dc.description.sponsorshipCanakkale Onsekiz Mart University, Grant/Award Number: COMU BAP, FDK-2017-1069; TUBA, Grant/Award Number: GEBIP-2008; Scientific Research Commission of Canakkale Onsekiz Mart University, Grant/Award Number: COMU BAP, FDK-2017-1069
dc.identifier.doi10.1002/pat.4097
dc.identifier.endpage159
dc.identifier.issn1042-7147
dc.identifier.issn1099-1581
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85021826440
dc.identifier.scopusqualityQ2
dc.identifier.startpage151
dc.identifier.urihttps://doi.org/10.1002/pat.4097
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24369
dc.identifier.volume29
dc.identifier.wosWOS:000418367000014
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPolymers For Advanced Technologies
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectcryogel
dc.subjectmicrogel
dc.subjectGA
dc.subjectHA natural polymer
dc.subjectgum Arabic cryogel
dc.subjecthydrogel
dc.subjecthemocompatible cryogel composite
dc.subjecthumic acid micro
dc.subjectnanogel
dc.titleHumic acid particle embedded super porous gum Arabic cryogel network for versatile use
dc.typeArticle

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