Investigation of endocrine and immunological response in fat tissue to hyperbaric oxygen administration in rats

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dc.authoridOztopuz, Ozlem/0000-0002-1373-6311
dc.authoriduzun, metehan/0000-0003-1406-5473
dc.contributor.authorSen, H.
dc.contributor.authorErbag, G.
dc.contributor.authorOvali, M. A.
dc.contributor.authorOztopuz, R. O.
dc.contributor.authorUzun, M.
dc.date.accessioned2025-01-27T20:22:54Z
dc.date.available2025-01-27T20:22:54Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThough HBO treatment is becoming more common, the mechanism of action is not fully known. The positive effects of HBO administration on the inflammatory response is thought to he a possible basic mechanism. As a result, we aimed to research whether endocrine and immunological response of tat tissue changes in rats given HBO treatment model. This research was carried out on Wistar albino rats, they were treated with hyperbaric Oxygen therapy. Their fatty tissue were taken from the abdomen, gene expression of the cytokines and adipokines mTere analyzed with Real time PCR method. When the gene expression of hormones and cytokines by fat tissue was examined, the leptin, visfatin, TNF-alpha, IL-1 beta and IL-10 levels in the HBO treatment group were statistically significantly increased compared to the control group (1)=0.0313, p=0.0156, p=0.0156, p=0.0156, p=0.0313). In conclusion, in our study we identified that HBO administration affected the endochrinological functions of fat tissue.
dc.description.sponsorshipCanakkale Onsekiz Mart University [TSA-2014-352]
dc.description.sponsorshipOur study was supported by the Research Fund of the Canakkale Onsekiz Mart University (project No.TSA-2014-352).
dc.identifier.doi10.14715/cmb/2016.62.5.3
dc.identifier.endpage19
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue5
dc.identifier.pmid27188864
dc.identifier.scopus2-s2.0-84994851469
dc.identifier.scopusqualityQ4
dc.identifier.startpage15
dc.identifier.urihttps://doi.org/10.14715/cmb/2016.62.5.3
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22065
dc.identifier.volume62
dc.identifier.wosWOS:000376592500004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherC M B Assoc
dc.relation.ispartofCellular and Molecular Biology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectHyperbaric oxygen treatment
dc.subjectfat tissue
dc.subjectadipokines
dc.subjectcytokines
dc.titleInvestigation of endocrine and immunological response in fat tissue to hyperbaric oxygen administration in rats
dc.typeArticle

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