Alterations of platelet function and coagulation parameters during acute pancreatitis

Basit Öğe Kaydı
dc.authoriddemirci, selim/0009-0006-3024-3267
dc.contributor.authorAkbal, Erdem
dc.contributor.authorDemirci, Selim
dc.contributor.authorKocak, Erdem
dc.contributor.authorKoklu, Seyfettin
dc.contributor.authorBasar, Omer
dc.contributor.authorTuna, Yasar
dc.date.accessioned2025-01-27T20:57:41Z
dc.date.available2025-01-27T20:57:41Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractVascular thrombosis and systemic hypercoagulable states are known complications of pancreatitis. Higher levels of mean platelet volume (MPV) have been associated with thrombotic diseases. However, a few studies have investigated the association between acute pancreatitis and MPV. We aimed to investigate whether there is a difference of MPV and coagulation parameters in patients with active and remission in acute pancreatitis. We included 24 consecutive patients with biliary acute pancreatitis and 24 consecutive healthy age-matched and sex-matched controls. Full blood counts and other laboratory tests were collected at onset and remission. The MPV was significantly higher in patients with acute pancreatitis at admission 8.6 +/- 1.4 fl than controls 7.6 +/- 0.7 fl (P=0.005). We detected positive correlation between, aspartate aminotransferase, alanine aminotransferase, g-glutamyltransferase, amylase, lipase, and glucose, BMI, D-dimer and MPV. However, there was negative correlation between progression, thrombocyte counts, hemoglobin and MPV. As a result higher MPV levels in acute pancreatitis may reflect hypercoagulation associated with pancreatitis. Blood Coagul Fibrinolysis 24:243-246 (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
dc.identifier.doi10.1097/MBC.0b013e32835aef51
dc.identifier.endpage246
dc.identifier.issn0957-5235
dc.identifier.issue3
dc.identifier.pmid23425662
dc.identifier.scopus2-s2.0-84875829618
dc.identifier.scopusqualityQ3
dc.identifier.startpage243
dc.identifier.urihttps://doi.org/10.1097/MBC.0b013e32835aef51
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26439
dc.identifier.volume24
dc.identifier.wosWOS:000316739900004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofBlood Coagulation & Fibrinolysis
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectacute pancreatitis
dc.subjectcoagulations parameters
dc.subjectmean platelet volume
dc.titleAlterations of platelet function and coagulation parameters during acute pancreatitis
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu