The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study

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dc.authorid0000-0001-9889-1064en_US
dc.authorscopusid15132952200en_US
dc.authorwosid-en_US
dc.contributor.authorCengiz, Gizem
dc.contributor.authorNas, Kemal
dc.contributor.authorKeskin, Yaşar
dc.contributor.authorKılıç, Erkan
dc.contributor.authorSargın, Betül
dc.contributor.authorAcer Kasman, Sevtap
dc.contributor.authorReşorlu, Hatice
dc.date.accessioned2024-01-24T06:47:38Z
dc.date.available2024-01-24T06:47:38Z
dc.date.issued2023en_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractAim: Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method: This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the χ2 test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results: In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion: We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement.en_US
dc.identifier.citationCengiz, G., Nas, K., Keskin, Y., Kılıç, E., Sargin, B., Kasman, S. A., … Tuncer, T. (2023). The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross‐sectional multicenter study. International Journal of Rheumatic Diseases, 26(1), 43–50. https://doi.org/10.1111/1756-185X.14442en_US
dc.identifier.doi10.1111/1756-185X.14442
dc.identifier.endpage50en_US
dc.identifier.issn1756-1841
dc.identifier.issn1756-185X
dc.identifier.issue1en_US
dc.identifier.pmid36165674
dc.identifier.scopus2-s2.0-85138726192
dc.identifier.startpage43en_US
dc.identifier.urihttps://doi.org/10.1111/1756-185X.14442
dc.identifier.urihttps://hdl.handle.net/20.500.12428/5364
dc.identifier.volume26en_US
dc.identifier.wosWOS:000859954300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorReşorlu, Hatice
dc.language.isoen
dc.publisherJohn Wiley and Sons Incen_US
dc.relation.ispartofInternational Journal of Rheumatic Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClinical characteristicsen_US
dc.subjectDisease activityen_US
dc.subjectNail involvementen_US
dc.subjectNail psoriasisen_US
dc.subjectPsoriatic arthritisen_US
dc.subjectQuality of lifeen_US
dc.titleThe impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
dc.typeArticle

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