Evaluation of iris epithelial and stromal thickness in patients with migraine by using optical coherence tomography

Basit Öğe Kaydı
dc.contributor.authorCam, Mustafa
dc.contributor.authorArikan, Sedat
dc.date.accessioned2025-01-27T20:47:24Z
dc.date.available2025-01-27T20:47:24Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: The amount of light reaching to the retina is an important factor for photophobia formation. Therefore, investigation of iris thickness in patients with migraine can be valuable for revealing their susceptibility to photophobia. In this study, it was aimed to evaluate the iris epithelial and stromal thickness, retinal ganglion cell layer (RGCL) thickness, and retinal nerve fibre layer (RNFL) thickness of patients with migraine. Methods: Forty-nine migraine patients (Group 1) and 50 control participants (Group 2) were included into this study. For obtaining standard measure in all participants, the epithelial and stromal thickness of dilatory and sphincter iris muscle was measured from the equal distance to the pupillary margin by using anterior segment mode of optical coherence tomography (AS-OCT). Additionally, RNFL and RGCL thicknesses were measured by using posterior segment mode of OCT (PS-OCT). Results: The epithelial thickness of iris sphincter muscle and the epithelial thickness of iris dilatory muscle was found to be significantly higher in patients with migraine compared to control subjects (p<0.001, p=0.001 respectively). Additionally the stromal thickness of both iris sphincter and iris dilatory muscle (p<0.001, p<0.001 respectively) as well as the total thickness of iris sphincter and iris dilatory muscle was significantly higher in patients with migraine than control subjects (p<0.001, p=0.02 respectively). However, no significant difference was found between patients with migraine and control subjects in terms of RNFL and RGCL thicknesses (p=0.1 and p=0.7 respectively). Conclusion: The finding of high epithelial and stromal iris thickness in patients with migraine may support the possible role of increased pupillary dynamic in photophobia formation.
dc.identifier.doi10.54029/2022kpy
dc.identifier.endpage160
dc.identifier.issn1823-6138
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85128428436
dc.identifier.scopusqualityQ4
dc.identifier.startpage153
dc.identifier.urihttps://doi.org/10.54029/2022kpy
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24881
dc.identifier.volume27
dc.identifier.wosWOS:000780777100017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAsean Neurological Assoc
dc.relation.ispartofNeurology Asia
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectMigraine
dc.subjectchoroid thickness
dc.subjectretinal nerve fibre layers
dc.titleEvaluation of iris epithelial and stromal thickness in patients with migraine by using optical coherence tomography
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu