Synthesis, structural aspects, and antimicrobial activity investigation of novel macrocyclic amide-containing compounds

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dc.authoridDulger, Basaran/0000-0002-3184-2652
dc.authoridKarabulut, H.R. Ferhat/0000-0002-9501-6296
dc.contributor.authorAghatabay, N. M.
dc.contributor.authorGunduz, S.
dc.contributor.authorBas, A.
dc.contributor.authorTurkyilmaz, M.
dc.contributor.authorKarabulut, H. R. F.
dc.contributor.authorDulger, B.
dc.date.accessioned2025-01-27T20:24:26Z
dc.date.available2025-01-27T20:24:26Z
dc.date.issued2012
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractMacrocyclic 1(6),7(6)-dimethyl-1,7(2,4)-ditriazina-2,6,8,12-tetraaza-3,5,9,11-tetraoxocyclododecaphane, 1(6),8(6)-dimethyl-1,8(2,4)-ditriazina-2,7,9,14-tetraaza-3,6,10,13-tetraoxocyclotetradecaphane, 1(6),9(6)-dimethyl-1,9(2,4)-ditriazina-2,8,10,16-tetraaza-3,7,11,15-tetraoxocyclohexadecaphane, and 1(6),10(6)-dimethyl-1,10(2,4)-ditriazina-2,9,11,18-tetraaza-3,8,12,17-tetraoxocyclooctadecaphane are synthesized. The compounds are characterized by elemental analyses, Raman, IR, H-1, C-13 NMR and mass spectral data. The antimicrobial activities of the compounds are evaluated against several bacteria and yeast cultures and the results were compared with those of commercial antibiotic and antifungal agents. Structure-activity relationships are also discussed.
dc.description.sponsorshipFatih University Scientific Research Center [P50020904_1]
dc.description.sponsorshipWe would like to extend our gratitude to the Fatih University Scientific Research Center for their financial support under project-P50020904_1.
dc.identifier.doi10.1007/s10593-012-1080-5
dc.identifier.endpage942
dc.identifier.issn0009-3122
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85028118613
dc.identifier.scopusqualityQ3
dc.identifier.startpage936
dc.identifier.urihttps://doi.org/10.1007/s10593-012-1080-5
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22222
dc.identifier.volume48
dc.identifier.wosWOS:000309660000017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofChemistry of Heterocyclic Compounds
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectantibiotic
dc.subjectmacrocycle
dc.subjectFT-Raman
dc.subjectphane system
dc.subjectphysicochemical
dc.subjectyeast
dc.titleSynthesis, structural aspects, and antimicrobial activity investigation of novel macrocyclic amide-containing compounds
dc.typeArticle

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