Effects of Supplementation with Iron, Selenium and Magnesium on Galleria mellonella Cell-Mediated Immune Responses
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Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Immune responses play a key role in the survival of all living things. Intake of inorganic materials is ofcritical importance in living organisms because of their participation in metabolism and some component ofcells. Iron (Fe), magnesium (Mg) and selenium (Se) were selected for this study because of their participation incritical constituents of cells, such as nucleic acids and enzymes in living organisms, and their indirect and directeffects on immunity. Although the separate effects of these inorganic materials are known, there is no study ontheir combined effects. Galleria mellonella, which is used as a model organism, is frequently used in evaluatingof effects of human pathogens due to its various properties. Total hemocyte counts and encapsulationmelanization responses are the most commonly observed parameters when examining the immune responsesof this model organism. In our study, the effects of the selected inorganic materials added in the ratio of 0.1%,0.25%, 0.5% and 1% in the nutrient content of G. mellonella on the immune responses of this organism wereinvestigated. As a result of the study, it was found that only 0.25% of the doses increased the hemocyte countand that the other doses significantly decreased compared to the control group. However, it was determinedthat 0.5% and 1% feeding caused a significant decrease in both hemocyte count and encapsulationmelanization responses. According to our findings, the nutrients which have over a certain dose by inorganicsubstances have negative effects on immunity.
Açıklama
Anahtar Kelimeler
Biyoloji, Genetik ve Kalıtım, İmmünoloji
Kaynak
Türk Tarım ve Doğa Bilimleri Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
3
