Digoxin intoxication: An old enemy in modern era

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dc.authoridErcan, Ertugrul/0000-0003-0480-4738
dc.authoridTURK, UGUR ONSEL/0000-0001-6348-6616
dc.authoridAsgun, H. Fatih/0000-0002-8969-5886
dc.contributor.authorKirilmaz, Bahadir
dc.contributor.authorSaygi, Serkan
dc.contributor.authorGungor, Hasan
dc.contributor.authorTurk, Ugur Onsel
dc.contributor.authorAlioglu, Emin
dc.contributor.authorAkyuz, Serdar
dc.contributor.authorAsgun, Fatih
dc.date.accessioned2025-01-27T20:11:53Z
dc.date.available2025-01-27T20:11:53Z
dc.date.issued2012
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjectives Although development of new treatment modalities limited digoxin usage, digoxin intoxication is still an important issue which could be easily overlooked. In this report, we analyzed a case series definitively diagnosed as digoxin intoxication in the modern era. Methods We analyzed 71 patients hospitalized with digoxin intoxication confirmed by history, complaints, clinical and electrocardiograph (ECG) findings, and serum digoxin levels > 2.0 ng/mL, during a five year period. The demographic and clinical data, indications for digoxin use, digoxin dosage, concurrent medications, laboratory data, hospital monitoring, and ECG findings were obtained from all patients. Results Thirty-eight of 71 patients (53.5%) had symptoms of heart failure during admission or later. Sixty-four percent of patients were older than 75 years. The percentage of females was 67%. Atrial fibrillation, hypertension and gastrointestinal complaints were more frequent in the females (64% in females, 30% in males, P = 0.007; 81% in female, 52% in males, P = 0.01; 50% in female, 17.3% in males, P = 0.008, respectively). The mortality rate during the hospital course was 7%. Conclusions This report demonstrated the reduced mortality rates in patients with digoxin intoxication over the study period. Gastrointestinal complaints are the most common symptoms in this population.
dc.identifier.doi10.3724/SP.J.1263.2012.01101
dc.identifier.endpage242
dc.identifier.issn1671-5411
dc.identifier.issue3
dc.identifier.pmid23097652
dc.identifier.scopus2-s2.0-84873742481
dc.identifier.scopusqualityQ2
dc.identifier.startpage237
dc.identifier.urihttps://doi.org/10.3724/SP.J.1263.2012.01101
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20767
dc.identifier.volume9
dc.identifier.wosWOS:000309522000004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherScience Press
dc.relation.ispartofJournal of Geriatric Cardiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectDigoxin intoxication
dc.subjectDigitalis
dc.subjectHeart failure
dc.subjectArrhythmia
dc.titleDigoxin intoxication: An old enemy in modern era
dc.typeArticle

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