Evaluation of Macular Ganglion Cell-inner Plexiform Layer and Choroid in Psoriasis Patients Using Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

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dc.contributor.authorErsan, Ismail
dc.contributor.authorKilic, Sevilay
dc.contributor.authorArikan, Sedat
dc.contributor.authorKara, Selcuk
dc.contributor.authorIsik, Selda
dc.contributor.authorGencer, Baran
dc.contributor.authorOgretmen, Zerrin
dc.date.accessioned2025-01-27T21:02:07Z
dc.date.available2025-01-27T21:02:07Z
dc.date.issued2017
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: To evaluate changes in the thickness of the central macula, macular ganglion cell-inner plexiform layer (mGCIPL), and subfoveal choroid in patients with psoriasis using spectral domain optical coherence tomography (SD-OCT). Methods: The measurements of macular, mGCIPL thicknesses and subfoveal choroidal thickness (SFCT) obtained by SD-OCT of psoriasis patients (n = 46). These measurements were compared with those of 50 healthy controls. Results: The macular, mGCIPL, and choroidal thicknesses did not differ between the controls and psoriatic subjects (p>0.05). When the patients were divided into two distinct groups, only the SFCT was significantly thicker in the severe psoriasis group compared with the mild psoriasis group (p = 0.003). Conclusions: These findings suggest that choroidal alterations are seen without macular changes in patients with psoriasis. Severe psoriasis appears to be related to increases in SFCT as a consequence of possible inflammatory cascades that are part of the disease's pathogenesis.
dc.identifier.doi10.3109/09273948.2016.1150493
dc.identifier.endpage524
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue4
dc.identifier.pmid27015161
dc.identifier.scopus2-s2.0-84961658035
dc.identifier.scopusqualityQ1
dc.identifier.startpage520
dc.identifier.urihttps://doi.org/10.3109/09273948.2016.1150493
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27286
dc.identifier.volume25
dc.identifier.wosWOS:000412790900011
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofOcular Immunology and Inflammation
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectChoroidal thickening
dc.subjectmacular ganglion cell layer
dc.subjectpsoriasis area and severity index
dc.subjectsystemic inflammation
dc.subjecttumor necrosis factor alpha
dc.titleEvaluation of Macular Ganglion Cell-inner Plexiform Layer and Choroid in Psoriasis Patients Using Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography
dc.typeArticle

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