An approach for prediction of optimum reaction conditions for laccase-catalyzed bio-transformation of 1-naphthol by response surface methodology (RSM)

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dc.authoridŞahiner, Nurettin / 0000-0003-0120-530X
dc.contributor.authorCeylan, Hasan
dc.contributor.authorKubilay, Şenol
dc.contributor.authorAktaş, Nahit
dc.contributor.authorŞahiner, Nurettin
dc.date.accessioned2025-01-27T20:52:08Z
dc.date.available2025-01-27T20:52:08Z
dc.date.issued2008
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractResponse surface methodology (RSM) was successfully applied to enzymatic bio-transformation of 1-naphthol. The experiments were conducted in a closed system containing acetone and sodium acetate buffer, with laccase enzyme. Laccase enzyme used as catalyst was derived from Trametes versicolor (ATCC 200801). The enzymatic bio-transformation rate of I-naphthol, based oil measurements of initial dissolved oxygen (DO) consumption rate in the closed system, was optimized by the application of RSM. The independent variables, which had been found as the most effective variables on the initial DO consumption rate by screening experiments, were determined as medium temperature, pH and acetone content. A quadratic model was developed through RSM in terms of related independent variables to describe the DO consumption rate as the response. Based on contour plots and variance analysis, optimum operational conditions for maximizing initial DO consumption rate, while keeping acetone content at its minimum value, were 301 K of temperature, pH 6 and acetone content of 7% to obtain 9.17 x 10(-3) mM DO/min for initial oxidation rate. (c) 2007 Published by Elsevier Ltd.
dc.identifier.doi10.1016/j.biortech.2007.03.018
dc.identifier.endpage2031
dc.identifier.issn0960-8524
dc.identifier.issue6
dc.identifier.pmid18053708
dc.identifier.scopus2-s2.0-37549060275
dc.identifier.scopusqualityQ1
dc.identifier.startpage2025
dc.identifier.urihttps://doi.org/10.1016/j.biortech.2007.03.018
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25669
dc.identifier.volume99
dc.identifier.wosWOS:000253015800069
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofBioresource Technology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectlaccase
dc.subject1-naphthol
dc.subjectenzymatic polymerization
dc.subjectresponse surface methodology
dc.subjectoptimization
dc.titleAn approach for prediction of optimum reaction conditions for laccase-catalyzed bio-transformation of 1-naphthol by response surface methodology (RSM)
dc.typeArticle

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