Fungal endophthalmitis and the effectiveness of moxifloxacin on fungal endophthalmitis therapy

dc.contributor.authorArikan, Sedat
dc.contributor.authorTufan, Hasan Ali
dc.date.accessioned2025-01-27T19:06:10Z
dc.date.available2025-01-27T19:06:10Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractFungal endophthalmitis is a rare clinical condition that can potentially cause severe visual loss, and it is easily misdiagnosed unless detailed ocular examination have been done by ophthalmologists. In this disease, the infectious agent can gain access into the vitreous cavity either by traumatic introduction (exogenous) or through hematogenous spread (endogenous). In the two forms of the fungal endophthalmitis, Candida albicans is the most common causative microorganism that is seen approximately 33%-85% in all. The successful treatment rate of fungal endophthalmitis is closely associated with early diagnose of the disorder and administration of the appropriate antifungal therapy. After the exploration of amphotericin B, fungal endophthalmitis has been treated successfully as good as the other fungal infections. Amphotericin B ise the most effective antifungal drug among all of them. However, since amphotericin B poses great risk of severe ocular and systemic toxicity, its usage is limited frequently. In the literature there are few investigation that reports the effectiveness of quinolone antibiotics in modulating the effects of antifungal drugs.
dc.identifier.endpage87
dc.identifier.issn1307-1173
dc.identifier.issue1
dc.identifier.scopus2-s2.0-84878411021
dc.identifier.scopusqualityN/A
dc.identifier.startpage80
dc.identifier.urihttps://hdl.handle.net/20.500.12428/14170
dc.identifier.volume7
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofAnatolian Journal of Clinical Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectAmphotericin b; Fungal endophthalmitis; Moxifloxacin
dc.titleFungal endophthalmitis and the effectiveness of moxifloxacin on fungal endophthalmitis therapy
dc.title.alternativeFungal endoftalmi?ler ve fungal endoftalmi? tedavi?si?nde moksi?floksasi?ni?n etki?si?
dc.typeArticle

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