Fungal endophthalmitis and the effectiveness of moxifloxacin on fungal endophthalmitis therapy
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Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Fungal endophthalmitis is a rare clinical condition that can potentially cause severe visual loss, and it is easily misdiagnosed unless detailed ocular examination have been done by ophthalmologists. In this disease, the infectious agent can gain access into the vitreous cavity either by traumatic introduction (exogenous) or through hematogenous spread (endogenous). In the two forms of the fungal endophthalmitis, Candida albicans is the most common causative microorganism that is seen approximately 33%-85% in all. The successful treatment rate of fungal endophthalmitis is closely associated with early diagnose of the disorder and administration of the appropriate antifungal therapy. After the exploration of amphotericin B, fungal endophthalmitis has been treated successfully as good as the other fungal infections. Amphotericin B ise the most effective antifungal drug among all of them. However, since amphotericin B poses great risk of severe ocular and systemic toxicity, its usage is limited frequently. In the literature there are few investigation that reports the effectiveness of quinolone antibiotics in modulating the effects of antifungal drugs.
Açıklama
Anahtar Kelimeler
Amphotericin b; Fungal endophthalmitis; Moxifloxacin
Kaynak
Anatolian Journal of Clinical Investigation
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
7
Sayı
1
