Temperament characteristics in patients with panic disorder and their first-degree relatives

Basit Öğe Kaydı
dc.authoridAydemir, Omer/0000-0003-3050-1263
dc.authoridGuloksuz, Sinan/0000-0002-6626-1874
dc.contributor.authorAltinbas, Gulcin
dc.contributor.authorAltinbas, Kurst
dc.contributor.authorGuloksuz, Selin Aktan
dc.contributor.authorGuloksuz, Sinan
dc.contributor.authorAydemir, Omer
dc.contributor.authorOzgen, Guliz
dc.date.accessioned2025-01-27T20:57:51Z
dc.date.available2025-01-27T20:57:51Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: Panic disorder is one of the highly heritable anxiety disorders; and temperament characteristics are considered predicting liability to panic disorder. Accumulating evidence suggests temperament characteristics are intermediate phenotypes for clinical conditions. Given this background, we aimed to investigate temperament characteristics in patients with panic disorder, their first-degree relatives, and healthy controls. Method: Study sample was consisted 60 patients with panic disorder, 37 first-degree relatives of these patients, and 37 age, gender, and education level matched healthy controls (HC). SCID-I, the Panic Agoraphobia Scale, and the State and Trait Anxiety Inventory were applied to assess clinical characteristics of the patient group. Temperament characteristics were assessed using the Temperament Evaluation of Memphis, Pisa, Paris, San Diego Autoquestionnaire (TEMPS-A). Results: Anxious, depressive, cyclothymic, and irritable temperament scores of patients were higher than those of HC. There was no difference between the patients and the relatives, with the exception of higher anxious temperament scores in patients. Conclusion: Overall, our findings suggest that anxious temperament characteristic might be a trait marker for liability to panic disorder. Further research with a prospective design in a larger sample is required to confirm our findings. (C) 2015 Elsevier Inc. All rights reserved.
dc.description.sponsorshipEuropean Community [HEALTH-F2-2009-241909]
dc.description.sponsorshipSinan Guloksuz would like to acknowledge the support of the European Community's Seventh Framework Programme under grant agreement no. HEALTH-F2-2009-241909 (Project EU-GEI).
dc.identifier.doi10.1016/j.comppsych.2015.03.008
dc.identifier.endpage77
dc.identifier.issn0010-440X
dc.identifier.issn1532-8384
dc.identifier.pmid25967357
dc.identifier.scopus2-s2.0-84930577128
dc.identifier.scopusqualityQ1
dc.identifier.startpage73
dc.identifier.urihttps://doi.org/10.1016/j.comppsych.2015.03.008
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26522
dc.identifier.volume60
dc.identifier.wosWOS:000356112600011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherW B Saunders Co-Elsevier Inc
dc.relation.ispartofComprehensive Psychiatry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectSerotonin Transporter Gene
dc.subjectHarm Avoidance
dc.subjectAnxious Temperament
dc.subjectAnxiety Proneness
dc.subjectCandidate Genes
dc.subjectPersonality
dc.subjectAssociation
dc.subjectDimensions
dc.subjectDepression
dc.subjectAmygdalar
dc.titleTemperament characteristics in patients with panic disorder and their first-degree relatives
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu