Preparation and characterization of ethylenediamine and cysteamine plasma polymerized films on piezoelectric quartz crystal surfaces for a biosensor

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dc.authoridShard, Alexander/0000-0002-8931-5740
dc.authoridGoktas, Hilal/0000-0003-2897-0036
dc.authoridMutlu, Mehmet/0000-0001-7146-1937
dc.authoridMutlu, Mehmet/0000-0001-9610-9817
dc.contributor.authorMutlu, Selma
dc.contributor.authorCoekeliler, Dilek
dc.contributor.authorShard, Alex
dc.contributor.authorGoktas, Hilal
dc.contributor.authorOzansoy, Berna
dc.contributor.authorMutlu, Mehmet
dc.date.accessioned2025-01-27T20:53:56Z
dc.date.available2025-01-27T20:53:56Z
dc.date.issued2008
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis paper describes a method for the modification of quartz crystal surfaces to be used as a transducer in biosensors that allow recognition and quantification of certain biomolecules (antibodies, enzymes, proteins, etc). Quartz crystal sensors were modified by a plasma based electron beam generator in order to detect the level of the toxin histamine within biological liquids (blood, serum) and food (wine, cheese, fish etc.). Cysteamine and ethylenediamine were used as precursors in the plasma. After each modification step, the layers on the quartz crystal were characterized by frequency measurements. Modified surfaces were also characterized by contact angle, X-ray photoelectron spectroscopy and atomic force microscopy to determine the physical and chemical characteristics of the surfaces after each modification. Finally, the performance of the sensors were tested by the response to histamine via frequency shifts. The frequency shifts of the sensors prepared by plasma polymerization of ethylenediamine and cysteamine were approximately 3230 Hz and 5630 Hz, respectively, whereas the frequency change of the unmodified crystal surface was around 575 Hz. (C) 2007 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.tsf.2007.06.074
dc.identifier.endpage1255
dc.identifier.issn0040-6090
dc.identifier.issue6
dc.identifier.scopus2-s2.0-37349132444
dc.identifier.scopusqualityQ2
dc.identifier.startpage1249
dc.identifier.urihttps://doi.org/10.1016/j.tsf.2007.06.074
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25908
dc.identifier.volume516
dc.identifier.wosWOS:000252980400061
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofThin Solid Films
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectquartz crystal
dc.subjectelectron beam
dc.subjectglow discharge
dc.subjectcysteamine
dc.subjectplasma polymerized films
dc.subjecthistamine
dc.titlePreparation and characterization of ethylenediamine and cysteamine plasma polymerized films on piezoelectric quartz crystal surfaces for a biosensor
dc.typeArticle

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