Which Exercise Type is Better on Autophagy in Older Adults?

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dc.contributor.authorCoşkun, Ali
dc.contributor.authorGünar, Bilgetekin Burak
dc.contributor.authorŞahin, Gülşah
dc.date.accessioned2025-01-27T20:04:25Z
dc.date.available2025-01-27T20:04:25Z
dc.date.issued2021
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAging is characterized by accumulation of damage in cellular components increasing fragility and risk of death caused by disruption of different biological processes. The autophagy is a basic cellular homeostasis process requiring different pathophysiologic conditions for degradation and recycling of damaged cellular organelles and proteins. This process, called autophagy, is a fundamental cellular homeostatic process required in different pathophysiological conditions for the degradation and recycling of damaged cellular organelles and proteins. During the aging process, the autophagy flux reduces. However, both animal and human studies show that exercise has positive effects on autophagy markers and flux within aging metabolism. The aim of this review is to answer a few questions such as “Which exercise stimulates autophagy more in aging?”, “What do the available human research results indicate?”, “How does aging affect autophagy?”, “What is the correlation between exercise, aging, autophagy and muscle mass?”. According to the research results, resistance exercises and endurance exercises affect autophagy in the aging process. Resistance exercises increase the autophagy flux and may prevent sarcopenia. Endurance exercises increase oxidative stress, which may increase autophagy flux and preserve mitochondria quality. There is a need for new studies to more clearly reveal the effects of both exercise types. However, it is well known at present that whatever exercise is performed, obesity, chronic diseases, menopause, initial autophagy level and content, fitness levels of elderly individuals, training status, mitochondria content, muscle mass and nutrition type may change the progress of autophagy.
dc.identifier.endpage132
dc.identifier.issn1308-0938
dc.identifier.issn2146-8885
dc.identifier.issue1
dc.identifier.startpage124
dc.identifier.trdizinid491078
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/491078
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20523
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürkiye Klinikleri Spor Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectBiyoloji
dc.subjectGeriatri ve Gerontoloji
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectHücre Biyolojisi
dc.subjectSpor Bilimleri
dc.subjectİmmünoloji
dc.titleWhich Exercise Type is Better on Autophagy in Older Adults?
dc.typeArticle

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