Which Exercise Type is Better on Autophagy in Older Adults?
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Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aging is characterized by accumulation of damage in cellular components increasing fragility and risk of death caused by disruption of different biological processes. The autophagy is a basic cellular homeostasis process requiring different pathophysiologic conditions for degradation and recycling of damaged cellular organelles and proteins. This process, called autophagy, is a fundamental cellular homeostatic process required in different pathophysiological conditions for the degradation and recycling of damaged cellular organelles and proteins. During the aging process, the autophagy flux reduces. However, both animal and human studies show that exercise has positive effects on autophagy markers and flux within aging metabolism. The aim of this review is to answer a few questions such as “Which exercise stimulates autophagy more in aging?”, “What do the available human research results indicate?”, “How does aging affect autophagy?”, “What is the correlation between exercise, aging, autophagy and muscle mass?”. According to the research results, resistance exercises and endurance exercises affect autophagy in the aging process. Resistance exercises increase the autophagy flux and may prevent sarcopenia. Endurance exercises increase oxidative stress, which may increase autophagy flux and preserve mitochondria quality. There is a need for new studies to more clearly reveal the effects of both exercise types. However, it is well known at present that whatever exercise is performed, obesity, chronic diseases, menopause, initial autophagy level and content, fitness levels of elderly individuals, training status, mitochondria content, muscle mass and nutrition type may change the progress of autophagy.
Açıklama
Anahtar Kelimeler
Biyoloji, Geriatri ve Gerontoloji, Biyokimya ve Moleküler Biyoloji, Hücre Biyolojisi, Spor Bilimleri, İmmünoloji
Kaynak
Türkiye Klinikleri Spor Bilimleri Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
13
Sayı
1
