Evaluation of Genotoxic Effect of Phloxine by Allium Test

dc.contributor.authorKaya, Nergis
dc.date.accessioned2025-01-27T19:26:37Z
dc.date.available2025-01-27T19:26:37Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPhloxine is used as a food dye. In this study, genotoxicity of phloxine at the root tip of Allium cepa\rL. was investigated. A. cepa L. meristematic root tip cells were treated with ten different doses of\rphloxine. In this way, the EC50 value was determined. Then, phloxine was applied to root tips at\rEC50/2, EC50 and EC50×2 doses. Treatment time was determined as 24, 48 and 72 hours. As a result,\rit was revealed that phloxine caused chromosomal aberrations in cells in mitotic cycle at the root tip\rof A. cepa. There are equatorial plate shifting in metaphase, laggard chromosome, disturbed spindle,\rchromosome stickiness, C-mitosis, polar shifting among the observed chromosomal aberrations. It\rwas stated that the % chromosomal aberration index (CAI) increased depending on concentration\rincrease. It has been demonstrated that the highest % chromosomal aberration index occurred at the\rEC50×2 dose for 72 hours. According to the research, it was revealed that phloxine has a genotoxic\reffect on the root cells of A. cepa. For this reason, it can be emphasized that care should be taken in\rits use in foods
dc.identifier.doi10.24925/turjaf.v10i4.637-641.4708
dc.identifier.endpage641
dc.identifier.issn2148-127X
dc.identifier.issue4
dc.identifier.startpage637
dc.identifier.trdizinid537096
dc.identifier.urihttps://doi.org/10.24925/turjaf.v10i4.637-641.4708
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/537096
dc.identifier.urihttps://hdl.handle.net/20.500.12428/15564
dc.identifier.volume10
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürk Tarım - Gıda Bilim ve Teknoloji dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectBiyoloji
dc.subjectKimya
dc.subjectTıbbi
dc.subjectGıda Bilimi ve Teknolojisi
dc.titleEvaluation of Genotoxic Effect of Phloxine by Allium Test
dc.typeArticle

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