Evaluation of Genotoxic Effect of Phloxine by Allium Test
[ X ]
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Phloxine is used as a food dye. In this study, genotoxicity of phloxine at the root tip of Allium cepa\rL. was investigated. A. cepa L. meristematic root tip cells were treated with ten different doses of\rphloxine. In this way, the EC50 value was determined. Then, phloxine was applied to root tips at\rEC50/2, EC50 and EC50×2 doses. Treatment time was determined as 24, 48 and 72 hours. As a result,\rit was revealed that phloxine caused chromosomal aberrations in cells in mitotic cycle at the root tip\rof A. cepa. There are equatorial plate shifting in metaphase, laggard chromosome, disturbed spindle,\rchromosome stickiness, C-mitosis, polar shifting among the observed chromosomal aberrations. It\rwas stated that the % chromosomal aberration index (CAI) increased depending on concentration\rincrease. It has been demonstrated that the highest % chromosomal aberration index occurred at the\rEC50×2 dose for 72 hours. According to the research, it was revealed that phloxine has a genotoxic\reffect on the root cells of A. cepa. For this reason, it can be emphasized that care should be taken in\rits use in foods
Açıklama
Anahtar Kelimeler
Biyoloji, Kimya, Tıbbi, Gıda Bilimi ve Teknolojisi
Kaynak
Türk Tarım - Gıda Bilim ve Teknoloji dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
10
Sayı
4
