The ischemia modified albumin and mean platelet volume levels in patients with Behcet's disease

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dc.authoridHIZ, Meliha Merve/0000-0003-4303-9717
dc.contributor.authorKilic, Sevilay
dc.contributor.authorIsik, Selda
dc.contributor.authorHiz, Meliha Merve
dc.contributor.authorCakir, Dilek Ulker
dc.contributor.authorTurkon, Hakan
dc.contributor.authorCevizci, Sibel
dc.contributor.authorOgretmen, Zerrin
dc.date.accessioned2025-01-27T20:49:45Z
dc.date.available2025-01-27T20:49:45Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Behcet's disease (BD) is a chronic inflammatory disorder with endothelial dysfunction. Ischemia-modified albumin (IMA) is a marker used in the detection of diseases associated with oxidative stress, vascular endothelial cell dysfunction and ischemia. Mean platelet volume (MPV) signifies the platelet function and activity. Aim: To show whether MPV and IMA are useful in revealing the oxidative stress and the risk of thrombosis in patients with BD. Material and methods: Twenty-six patients with BD and 28 healthy volunteers as a control group over 18 years of age were included in the study. Serum IMA and MPV levels were analyzed in both groups. Results: The mean MPV values were identified as 0.86 +/- 0.15 and 0.82 +/- 0.08 (in the BD and control groups, respectively; p = 0.188) and the mean IMA values were 9.39 +/- 0.73 and 9.17 +/- 1.09 (in the BD and control groups, respectively; p = 0.275). There were no statistically significant differences between the groups. The IMA values of BD patients who were in the active phase were significant as compared to inactive BD patients and control groups (p = 0.041). The IMA and MPV values of the thrombotic patients, non-thrombotic patients and control groups were not significant. Conclusions: Ischemia-modified albumin may be a helpful marker of possible complications during an active period of BD.
dc.identifier.doi10.5114/ada.2016.62840
dc.identifier.endpage348
dc.identifier.issn1642-395X
dc.identifier.issue5
dc.identifier.pmid27881940
dc.identifier.scopus2-s2.0-84992390125
dc.identifier.scopusqualityQ2
dc.identifier.startpage345
dc.identifier.urihttps://doi.org/10.5114/ada.2016.62840
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25300
dc.identifier.volume33
dc.identifier.wosWOS:000386539100006
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltd
dc.relation.ispartofPostepy Dermatologii I Alergologii
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectBehcet's disease
dc.subjectischemia-modified albumin
dc.subjectmean platelet volume
dc.titleThe ischemia modified albumin and mean platelet volume levels in patients with Behcet's disease
dc.typeArticle

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