Seroprevalence of Hepatitis E in Hospital Employees and Investigation of Risk Factors

Basit Öğe Kaydı
dc.contributor.authorCakmak-Topfedaisi, Ozlem
dc.contributor.authorSener, Alper
dc.date.accessioned2025-01-27T20:26:59Z
dc.date.available2025-01-27T20:26:59Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: There are few epidemiologic case-control studies in Turkey about hepatitis E virus (HEV). Seroprevalence and risk factor studies will guide vaccination recommendations in our country. It was aimed to detect HEV antibodies and to investigate the risk factors for hepatitis E in the cleaning staff of Canakkale Onsekiz Mart University Hospital for Medical Research and Practice. Methods: 90 cleaning staff working at the canakkale Onsekiz Mart University Hospital and 90 administrative staff were included in the study group. The presence of HEV IgG and IgM antibodies were investigated by micro-ELISA. HEV-RNA was investigated in IgG-positive patients. Known and predicted risk factors for fecal -orally transmitted infections were included in questionnaires. Correlation analysis between groups was made in terms of age, gender, education, number of rooms in their house, number of residents in their house, source of drinking and domestic water, history of jaundice, surgery, blood transfusion and chronic disease (including drug use), and use of common items. Open-ended questions were used for investigation of possible risk factors. Results: Anti-HEV IgG was positive in 13 (7.2%) subjects. None of them showed anti-HEV IgM positivity. REV RNA positivity was not detected. The relationship between seropositivity and being over 45 years old, having more than five siblings, and having less than two rooms in the house were statistically significant (p<0.005). Seropositivity was found as high as 18% in the group with poor socioeconomic status. There was no significant relationship between seropositivity and gender, socioeconomic status, education level, number of rooms, history of jaundice and source of drinking water, There was no difference between each groups in the answers to the open-ended questions. Conclusions: Being over 45 years old, living in crowded and small homes increase the risk of HEV infection.
dc.identifier.doi10.5152/kd.2020.09
dc.identifier.endpage51
dc.identifier.issn1301-143X
dc.identifier.issn1309-1484
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85089203206
dc.identifier.scopusqualityQ4
dc.identifier.startpage44
dc.identifier.urihttps://doi.org/10.5152/kd.2020.09
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22534
dc.identifier.volume33
dc.identifier.wosWOS:000531866700010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAves
dc.relation.ispartofKlimik Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectHepatitis E virus
dc.subjectcleaning staff
dc.titleSeroprevalence of Hepatitis E in Hospital Employees and Investigation of Risk Factors
dc.title.alternativeHastane çalışanlarında hepatit E seroprevalansı ve risk faktörlerinin araştırılması
dc.typeArticle

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