Electrocatalytic Oxidation of NADH Using a Pencil Graphite Electrode Modified with Hematoxylin

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dc.authoridGiray Dilgin, Didem/0000-0002-3487-3470
dc.authoridDilgin, Yusuf/0000-0002-2980-6871
dc.contributor.authorDilgin, Yusuf
dc.contributor.authorErtek, Bensu
dc.contributor.authorKizilkaya, Bayram
dc.contributor.authorDilgin, Didem Giray
dc.contributor.authorGokcel, H. Ismet
dc.date.accessioned2025-01-27T20:17:21Z
dc.date.available2025-01-27T20:17:21Z
dc.date.issued2012
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn the present study, the electrocatalytic oxidation of reduced p-Nicotinamide Adenine Dinucleotide (NADH) was investigated using a pencil graphite electrode modified with hematoxylin (PGE/HMT). The PGE/HMT was prepared by adsorption of HMT on the PGE via immersion of bare PGE into 1.0 mM HMT solution (in methanol) for 60 s at room temperature. Cyclic voltammetric studies show that the peak potential of NADH oxidation shifts from +450 mV at bare PGE to +200 mV at PGE/HMT. The electrocatalytic currents obtained from the amperometric measurements at +200 mV versus Ag/AgCl/KClsat and pH 7.0 phosphate buffer solution containing 0.1 M KCl were linearly related to the concentration of NADH. The calibration graph consisted of two linear segments of 0.5-10 mu M and 10-300 mu M with a detection limit of 0.2 mu M (based on 3s(b), s(b) is the standard deviation of the blank response). The amperometric measurements exhibited that the response of the modified PGE/HMT towards the oxidation of NADH is reproducible, fast, sensitive and stable. Finally, the results obtained in the present study conclusively show that PGE modified with HMT can be effectively used to detect NADH.
dc.identifier.doi10.1166/sam.2012.1376
dc.identifier.endpage927
dc.identifier.issn1947-2935
dc.identifier.issn1947-2943
dc.identifier.issue9
dc.identifier.scopus2-s2.0-84871187349
dc.identifier.scopusqualityN/A
dc.identifier.startpage920
dc.identifier.urihttps://doi.org/10.1166/sam.2012.1376
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21555
dc.identifier.volume4
dc.identifier.wosWOS:000311255100004
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmer Scientific Publishers
dc.relation.ispartofScience of Advanced Materials
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectElectrocatalytic Oxidation
dc.subjectHematoxylin
dc.subjectNADH
dc.subjectPencil Graphite Electrode
dc.titleElectrocatalytic Oxidation of NADH Using a Pencil Graphite Electrode Modified with Hematoxylin
dc.typeArticle

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