Determination of antioxidant, antimicrobial and antitumor activity of bryophytes from Mount Ida (Canakkale, Turkey)

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dc.contributor.authorYayintas, Ozlem Tonguc
dc.contributor.authorYilmaz, Selehattin
dc.contributor.authorSokmen, Munevver
dc.date.accessioned2025-01-27T20:29:32Z
dc.date.available2025-01-27T20:29:32Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn this study, active components of bryophytes were extracted from the samples collected from Mount Ida (Canakkale-Turkey). Three different extraction methods (Soxhlet, supercritical fluid extraction-SFE, Soxhlet after SFE) were employed for 2016 samples while direct Soxhlet extraction was carried out for 2017 samples using methanol as extracting solvent. Initially, antioxidant activity tests of the crude extracts were performed for all the samples. Antioxidant properties were determined to be fairly weak or moderate in the majority of the species studied. Marchantia polymorpha (T1), a liverwort, showed high extraction yield and antioxidant activity. Similarly, high activity was detected in Hypnum cupressiforme (T9) and Neckera complanata (T10) species. The antioxidant capacity of the tested species often sheds light on other activities. Antimicrobial properties were also tested for all extracts obtained in 2017. Thuidium tamariscinum (T8) was positive against Acinetobacter haemolyticus ATCC 19002 bactericin; T1 and Isothceum myurum (T11) were positive against Bacillus subtilis TCC6633 bacteria and all other species were negative. Following these results, we have concentrated on the most active species and carried out antitumoral tests. Again, fractioned polar isolate of T1 was the only antiproliferative species against HeLa and A549 lung cancer cells.
dc.description.sponsorshipScientific Research Commission of Canakkale Onsekiz Mart University (COMU BAP) [FBA-2016-924]
dc.description.sponsorshipThis work is supported by the Scientific Research Commission of Canakkale Onsekiz Mart University (COMU BAP, FBA-2016-924).
dc.identifier.endpage401
dc.identifier.issn0972-5938
dc.identifier.issn0975-1068
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85071636222
dc.identifier.scopusqualityQ2
dc.identifier.startpage395
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22976
dc.identifier.volume18
dc.identifier.wosWOS:000500705900025
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherNatl Inst Science Communication-Niscair
dc.relation.ispartofIndian Journal of Traditional Knowledge
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectAntimicrobial
dc.subjectAntioxidant
dc.subjectAntitumor activity
dc.subjectBryophyte
dc.titleDetermination of antioxidant, antimicrobial and antitumor activity of bryophytes from Mount Ida (Canakkale, Turkey)
dc.typeArticle

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