Helicobacter pylori Seropositivity in Patients with Acute Coronary Syndromes

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dc.authoridErcan, Ertugrul/0000-0003-0480-4738
dc.authoridTURK, UGUR ONSEL/0000-0001-6348-6616
dc.contributor.authorTamer, Gulden S.
dc.contributor.authorTengiz, Istemihan
dc.contributor.authorErcan, Ertugrul
dc.contributor.authorDuman, Can
dc.contributor.authorAlioglu, Emin
dc.contributor.authorTurk, Ugur O.
dc.date.accessioned2025-01-27T20:11:53Z
dc.date.available2025-01-27T20:11:53Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe aim of this study was to investigate the seroprevalence of Helicobacter pylori (HP) in patients with coronary atherosclerosis and acute coronary syndromes. We enrolled 152 patients (group I, 73 patients with acute coronary syndrome; group II, 79 patients with chronic stable angina) and 22 control subjects. An enzyme-linked immunosorbent assay for immunoglobulin (Ig) G test for HP diagnosis was used on all enrolled subjects. C-reactive protein (CRP) was also measured in all patients as an inflammatory marker. Seropositivity rates for HP were significantly higher in patients with coronary artery disease than in controls (80.2% versus 54.5%; P < 0.05). Although CRP level was significantly higher in group I than in group II (1.72 +/- A 2.89 mg/dl versus 0.53 +/- A 0.63 mg/dl, P < 0.0001), HP infection rates were similar between groups (86.3% versus 74.6%, P > 0.05). Infection with HP may influence atherogenesis through low-grade, persistent inflammatory stimulation. However, our data show evidence of increased systemic inflammation in patients with acute coronary syndrome, which was unrelated to an increased HP seropositivity.
dc.identifier.doi10.1007/s10620-008-0482-9
dc.identifier.endpage1256
dc.identifier.issn0163-2116
dc.identifier.issn1573-2568
dc.identifier.issue6
dc.identifier.pmid18770033
dc.identifier.scopus2-s2.0-67349142967
dc.identifier.scopusqualityQ1
dc.identifier.startpage1253
dc.identifier.urihttps://doi.org/10.1007/s10620-008-0482-9
dc.identifier.urihttps://hdl.handle.net/20.500.12428/20768
dc.identifier.volume54
dc.identifier.wosWOS:000265880500014
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofDigestive Diseases and Sciences
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectHelicobacter pylori
dc.subjectCoronary artery disease
dc.subjectAcute coronary syndromes
dc.titleHelicobacter pylori Seropositivity in Patients with Acute Coronary Syndromes
dc.typeArticle

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