A critical review of molecularly imprinted polymer technology for aflatoxin sensing: Current status and future directions

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dc.contributor.authorCetinkaya, Ahmet
dc.contributor.authorKaya, S. Irem
dc.contributor.authorDemirbakan, Burcak
dc.contributor.authorUnal, Mehmet Altay
dc.contributor.authorSezginturk, Mustafa Kemal
dc.contributor.authorOzkan, Sibel A.
dc.contributor.authorAltuntas, Evrim Gunes
dc.date.accessioned2026-02-03T12:02:41Z
dc.date.available2026-02-03T12:02:41Z
dc.date.issued2026
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractSince the first discovery and identification of aflatoxins almost 70 years ago, their occurrence, potential risks, and health hazards remain of great importance. Therefore, several chromatography-, colorimetry-, and immunoassay-based analytical applications for aflatoxin detection are reported in the literature. Molecularly imprinted polymers (MIPs) have attracted considerable interest in sensor design due to their unique potential as synthetic recognition elements, providing high selectivity and excellent stability. These features help overcome the disadvantages of conventional sensing systems. The ongoing advancement of MIP-based sensors presents new opportunities for future applications and offers a reliable and versatile approach to meet the growing demands of current analytical research. This review focuses on studies published since 2023 concerning the detection of aflatoxins using MIP-based sensors, which hold a prominent and critical position in the literature. Additionally, this review addresses several limitations of MIP-based sensors, particularly in the context of aflatoxin detection, and discusses proposed solutions to overcome these challenges. Lastly, current advancements and future expectations in the topic are also highlighted.
dc.description.sponsorshipBAP-ADEP (Research Universities Support Program) [FBA-2023-2599]
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK) [BIDEB/2218]
dc.description.sponsorshipThis study was financially supported by BAP-ADEP (Research Universities Support Program) (Project Number: FBA-2023-2599) , and we greatly acknowledge this assistance. Ahmet Cetinkaya thanks the financial support from the Scientific and Technological Research Council of Turkiye (TUBITAK) under the BIDEB/2218-National Postdoctoral Research Scholarship Program.
dc.identifier.doi10.1016/j.jpba.2025.117330
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.pmid41485379
dc.identifier.scopus2-s2.0-105027111087
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2025.117330
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34827
dc.identifier.volume271
dc.identifier.wosWOS:001660032700001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Pharmaceutical and Biomedical Analysis
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260130
dc.subjectAflatoxins
dc.subjectMolecularly imprinted polymer
dc.subjectBiosensors
dc.subjectElectrochemical sensors
dc.subjectOptical sensors
dc.subjectReal samples
dc.titleA critical review of molecularly imprinted polymer technology for aflatoxin sensing: Current status and future directions
dc.typeReview

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