Prediction of Head-Up Tilt Test Result: Is it Possible?

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dc.authoridErcan, Ertugrul/0000-0003-0480-4738
dc.authoridTURK, UGUR ONSEL/0000-0001-6348-6616
dc.contributor.authorTurk, Ugur
dc.contributor.authorAlioglu, Emin
dc.contributor.authorKirilmaz, Bahadir
dc.contributor.authorDuygu, Hamza
dc.contributor.authorTuzun, Nurullah
dc.contributor.authorTengiz, Istemihan
dc.contributor.authorZoghi, Mehdi
dc.date.accessioned2025-01-27T20:47:24Z
dc.date.available2025-01-27T20:47:24Z
dc.date.issued2010
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: The determination of early, accurate, predictive criteria for a positive result would permit a reduction in the duration of the head-up tilt testing (HUTT). Previous studies propounded that existence of early sympathetic overreactivity (rapid and sustained increase in heart rate) during HUTT predicts positive result. However, the exact value of this variable is unknown. We analyzed the early heart rate (HR) responses to HUTT and evaluated their ability to predict HUTT result. Methods: Consecutive patients referred to the syncope unit of our center for recurrent unexplained syncope were studied. Results: We studied 189 consecutive patients and 67 (35%) patients had a negative HUTT; 122 (65%) patients had a positive HUTT. The early HR increase was defined as the maximum HR during the first 10 minutes of tilting minus the resting HR before tilting. The receiver-operator curves (ROCs) show the overall performance of the HR changes for predicting the HUTT result. For all variables, area under the ROC curve (AUC) was nearly equivalent to 0.50 and early HR increase was not a predictor of the negative result of HUTT (AUC = 0.546). Also there was no any significant correlation between the magnitude of early HR increase and patient age (r = -0.03, P = 0.76). Conclusions: The results suggest that the early increase in HR during the first 10 minutes of the HUTT may not be a useful parameter for predicting the test result. Many factors, such as late exaggeration in sympathetic activity during HUTT and age-dependent reduction in baroreflex sensitivity, may attenuate the predictive value of early HR increase. (PACE 2010; 33:153-158).
dc.identifier.doi10.1111/j.1540-8159.2009.02605.x
dc.identifier.endpage158
dc.identifier.issn0147-8389
dc.identifier.issue2
dc.identifier.pmid19889180
dc.identifier.scopus2-s2.0-75849145760
dc.identifier.scopusqualityQ3
dc.identifier.startpage153
dc.identifier.urihttps://doi.org/10.1111/j.1540-8159.2009.02605.x
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24890
dc.identifier.volume33
dc.identifier.wosWOS:000273901500009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-Blackwell Publishing, Inc
dc.relation.ispartofPace-Pacing and Clinical Electrophysiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectvagal syndromes
dc.subjectdata analysis
dc.titlePrediction of Head-Up Tilt Test Result: Is it Possible?
dc.typeArticle

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