Evaluation of the potential roles of activin-A, activin-B, and follistatin molecules exhibiting immunomodulatory properties in brucellosis

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dc.authorid0000-0003-3658-0185en_US
dc.authorscopusid57218293761en_US
dc.authorwosidCLW-1910-2022en_US
dc.contributor.authorKızmaz, Muhammed Ali
dc.contributor.authorEllergezen, Pinar Hiz
dc.contributor.authorDemir, Nesrin
dc.contributor.authorÇağan, Eren
dc.contributor.authorAkalın, Emin Halis
dc.contributor.authorOral, Haluk Barbaros
dc.contributor.authorBudak, Ferah
dc.date.accessioned2022-08-17T11:28:03Z
dc.date.available2022-08-17T11:28:03Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractBrucellosis is a zoonotic disease caused by bacteria called Brucella. The mechanisms underlying the changes seen in the course of brucellosis are not adequately elucidated. It was aimed to reveal the potential roles of activin‐A, activin‐B, and follistatin molecules in sera taken from patients with acute and chronic brucellosis, healthy controls, and recovered individuals to overcome these deficiencies. Activins are members of the transforming growth factor‐1 (TGF‐β1) superfamily. Activin‐A has been shown to play a role in both pro‐ inflammatory and anti‐inflammatory processes. Follistatin is a protein that inhibits or neutralizes the functions of activins, and in this way, it can regulate the inflammatory process.en_US
dc.identifier.citationKızmaz, M. A., Ellergezen, P. H., Demir, N., Çağan, E., Akalın, E. H., Oral, H. B., Budak, F., (2021). Evaluation of the potential roles of activin-A, activin-B, and follistatin molecules exhibiting immunomodulatory properties in brucellosis. European Journal of Immunology, 51(SUP1), 318-318.en_US
dc.identifier.endpage318en_US
dc.identifier.issn0014-2980
dc.identifier.issn1521-4141
dc.identifier.issueSUP1en_US
dc.identifier.startpage318en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12428/3672
dc.identifier.volume51en_US
dc.identifier.wosWOS:000753366401507
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.institutionauthorDemir, Nesrin
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofEuropean Journal of Immunologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectImmune response tracingen_US
dc.subjectInfectious diseaseen_US
dc.subjectInflammatory moleculesen_US
dc.titleEvaluation of the potential roles of activin-A, activin-B, and follistatin molecules exhibiting immunomodulatory properties in brucellosis
dc.typeConference Object

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