Long Term Sustained Therapeutic Effects of Percutaneous Posterior Tibial Nerve Stimulation Treatment of Neurogenic Overactive Bladder in Multiple Sclerosis Patients: 12-Months Results

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dc.authoridcanbaz kabay, sibel/0000-0003-4808-2191
dc.authoridsevim, mehmet/0000-0002-7571-7669
dc.contributor.authorKabay, Sibel Canbaz
dc.contributor.authorKabay, Sahin
dc.contributor.authorMestan, Emine
dc.contributor.authorCetiner, Mustafa
dc.contributor.authorAyas, Selahattin
dc.contributor.authorSevim, Mehmet
dc.contributor.authorOzden, Hilmi
dc.date.accessioned2025-01-27T20:59:54Z
dc.date.available2025-01-27T20:59:54Z
dc.date.issued2017
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAims: The aim of this study is to determine the sustained therapeutic efficacy and treatment intervals for PTNS in NOAB with MS, offering periodic additional treatments during 1 year in patients who completed an initial course of 12 consecutive weekly sessions. Methods: A total of 34 patients enrolled to the PTNS treatment and 21 patients completed the 1 year PTNS treatment with a tapering protocol of 6, 9, and 12 months of therapy, respectively. After 12 weeks of therapy, PTNS was applied at 14 day intervals for 3 months, 21 day intervals for 3 months, and 28 day intervals for 3 months. The patients completed a 3-day voiding diary at 3rd, 6th, 9th, and 12th month. The patients requested to complete validated questionnaires (ICIQ-SF, OAB-V8, OAB-q SF) were carried out within 3-month intervals thereafter during their enrolment in the study. Results: A total of 21 patients were enrolled in the study. Of these 5 (23.8%) were men and 16 (76.2%) women. The improvements for all voiding diary parameters were significant in the 6th, 9th, and 12th months when compared with baseline. Mean values between baseline and 12 month parameters suggested that daytime frequency decreased by 5.4 voids daily, urge incontinence decreased by 3.4 episodes daily, urgency episodes decreased by 7.4 episodes daily, nocturia decreased by 2.6 voids, and voided volume improved by a mean of 72.1 cc. Conclusion: These results have demonstrated NOAB symptom improvement in MS patients can be achieved with 12 weekly PTNS treatments which show excellent durability over 12 months. (C) 2015 Wiley Periodicals, Inc.
dc.identifier.doi10.1002/nau.22868
dc.identifier.endpage110
dc.identifier.issn0733-2467
dc.identifier.issn1520-6777
dc.identifier.issue1
dc.identifier.pmid26352904
dc.identifier.scopus2-s2.0-84941313056
dc.identifier.scopusqualityQ2
dc.identifier.startpage104
dc.identifier.urihttps://doi.org/10.1002/nau.22868
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26873
dc.identifier.volume36
dc.identifier.wosWOS:000394666500015
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofNeurourology and Urodynamics
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectelectrical stimulation
dc.subjectmultiple sclerosis
dc.subjectneuromodulation
dc.subjectPTNS
dc.subjecturinary incontinence
dc.subjecturodynamics
dc.titleLong Term Sustained Therapeutic Effects of Percutaneous Posterior Tibial Nerve Stimulation Treatment of Neurogenic Overactive Bladder in Multiple Sclerosis Patients: 12-Months Results
dc.typeArticle

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