Anthocyanins, Vibrant Color Pigments, and Their Role in Skin Cancer Prevention

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dc.authoridSocaciu, Carmen/0000-0002-7352-5057
dc.authoridDanciu, Corina/0000-0001-5999-1214
dc.authoridLeopold, Nicolae/0000-0002-2174-8064
dc.authoridAYVAZ, Zayde/0000-0002-8102-0577
dc.authoridAyvaz, Huseyin/0000-0001-9705-6921
dc.authoridDiaconeasa, Zorita/0000-0002-5325-3859
dc.authoridXiao, Jianbo/0000-0003-3311-770X
dc.contributor.authorDiaconeasa, Zorita
dc.contributor.authorStirbu, Ioana
dc.contributor.authorXiao, Jianbo
dc.contributor.authorLeopold, Nicolae
dc.contributor.authorAyvaz, Zayde
dc.contributor.authorDanciu, Corina
dc.contributor.authorAyvaz, Huseyin
dc.date.accessioned2025-01-27T20:50:10Z
dc.date.available2025-01-27T20:50:10Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractUntil today, numerous studies evaluated the topic of anthocyanins and various types of cancer, regarding the anthocyanins' preventative and inhibitory effects, underlying molecular mechanisms, and such. However, there is no targeted review available regarding the anticarcinogenic effects of dietary anthocyanins on skin cancers. If diagnosed at the early stages, the survival rate of skin cancer is quite high. Nevertheless, the metastatic form has a short prognosis. In fact, the incidence of melanoma skin cancer, the type with high mortality, has increased exponentially over the last 30 years, causing the majority of skin cancer deaths. Malignant melanoma is considered a highly destructive type of skin cancer due to its particular capacity to grow and spread faster than any other type of cancers. Plants, in general, have been used in disease treatment for a long time, and medicinal plants are commonly a part of anticancer drugs on the market. Accordingly, this work primarily aims to emphasize the most recent improvements on the anticarcinogenic effects of anthocyanins from different plant sources, with an in-depth emphasis on melanoma skin cancer. We also briefly summarized the anthocyanin chemistry, their rich dietary sources in flowers, fruits, and vegetables, as well as their associated potential health benefits. Additionally, the importance of anthocyanins in topical applications such as their use in cosmetics is also given.
dc.description.sponsorshipRomanian Ministry of Research and Innovation, CCCDI-UEFISCDI within PNCDI III [PN-III-P1-1.2-PCCDI-2017-0056]
dc.description.sponsorshipThe authors acknowledge support from the Romanian Ministry of Research and Innovation, CCCDI-UEFISCDI, project number PN-III-P1-1.2-PCCDI-2017-0056 within PNCDI III.
dc.identifier.doi10.3390/biomedicines8090336
dc.identifier.issn2227-9059
dc.identifier.issue9
dc.identifier.pmid32916849
dc.identifier.scopus2-s2.0-85091867965
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3390/biomedicines8090336
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25427
dc.identifier.volume8
dc.identifier.wosWOS:000581532400001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofBiomedicines
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectanthocyanins
dc.subjectcancer
dc.subjectdietary source
dc.subjectin vitro
dc.subjectmelanoma
dc.subjectskin
dc.titleAnthocyanins, Vibrant Color Pigments, and Their Role in Skin Cancer Prevention
dc.typeReview Article

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