Electrocatalytic oxidation of moxifloxacin hydrochloride on modified glassy carbon surface and determination in Avelox tablets

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dc.contributor.authorSadikoglu, M.
dc.contributor.authorSoylu, U.I.
dc.contributor.authorYilmaz, S.
dc.contributor.authorSelvi, B.
dc.contributor.authorYildiz Seckin, H.
dc.contributor.authorNosal-Wiercinska, A.
dc.date.accessioned2025-01-27T19:04:13Z
dc.date.available2025-01-27T19:04:13Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis work presents an electroanalytical method for the determination of moxifloxacin hydrochloride (MOX) in tablets. The surface of the glassy carbon electrode (GCE) was modified by electrochemical polymerization of 4-aminobenzene sulfonic acid in phosphate buffer solution (pH 7.0).The oxidative behavior of MOX was studied at glassy carbon and modified glassy carbon electrodes in different buffer systems using the cyclic voltammetry technique. The modified glassy carbon electrode (poly(4-ABSA/GCE) has very high catalytic ability for electrooxidation of MOX. Acetate buffer (pH 5.0) was selected as the optimum medium for the oxidation of MOX at poly(4-ABSA/GCE) due to the highest electronic signal increase obtained. Differential pulse voltammetry (DPV) and chronoamperometry (CA) techniques were used for voltammetric determination of MOX. The values of limit of detection (LOD) and limit of quantification (LOQ) were determined to be 3.19×10 -7 M and 1.06×10 -6 M for DPV; and 5.50×10 -7 M and 1.83×10 -6 M for CA, respectively. A highly sensitive electroanalytical method for the determination of MOX in Avelox tablets by DPV was described. © 2019 Bulgarian Academy of Sciences, Union of Chemists in Bulgaria
dc.description.sponsorshipGaziosmanpasa University Scientific Research Fund, (2016/76); Gaziosmanpasa Üniversitesi
dc.identifier.endpage133
dc.identifier.issn0861-9808
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85065125849
dc.identifier.scopusqualityQ4
dc.identifier.startpage125
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13868
dc.identifier.volume51
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBulgarian Academy of Sciences
dc.relation.ispartofBulgarian Chemical Communications
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subject4-Aminobenzene sulfonic acid; Electrocatalytic ability; Electropolymerization; Modified glassy carbon electrode; Moxifloxacin hydrochloride; Voltammetry
dc.titleElectrocatalytic oxidation of moxifloxacin hydrochloride on modified glassy carbon surface and determination in Avelox tablets
dc.typeArticle

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