A new practice of trichloroaceticacid peeling: reduction of second primary skin cancer

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dc.contributor.authorAvci, Gulden
dc.contributor.authorAkoz, Tayfun
dc.contributor.authorGul, Aylin Ege
dc.date.accessioned2025-01-27T21:21:38Z
dc.date.available2025-01-27T21:21:38Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: Exposure to solar radiation is a major cause of non-melanoma skin cancer. Topical application of chemical peeling agents to reverse actinic damage of skin is a well-established, accepted clinical practice. Subclinic malignant lesions are generally seen with skin cancers simultaneously. In this paper, we evaluated effectiveness of the tricholoroacetic acid peeling to treatment of subclinic lesions. Material and Methods: Between 1999 and 2004, 102 patients with skin cancer were treated surgically. In addition to the surgical treatment of malignant lesions, full-face chemical peeling with 35-40% trichloroacetic acid was applied during the same operative session to 48 patients whose faces had extensively sun-damaged skin. The ages of patients were varied between 51 and 93. They were followed-up 1-5 years. The effectiveness of the TCA treatment was evaluated with pathologic examinations. Result: Second primary skin cancer was observed in only 3 patients who were applied TCA peeling. TCA peeling causes histologic changes such as correction of epidermal atrophy and atypia as well as deposition of new subepidermal collagen. Conclusion: Trichloroaceticacid peeling provides a prophylactic effect against the development of skin malignancies.
dc.identifier.endpage61
dc.identifier.issn2564-6850
dc.identifier.issn2564-7032
dc.identifier.issue2
dc.identifier.scopus2-s2.0-70349210362
dc.identifier.scopusqualityQ3
dc.identifier.startpage56
dc.identifier.urihttps://hdl.handle.net/20.500.12428/29020
dc.identifier.volume25
dc.identifier.wosWOS:000420175000004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAves
dc.relation.ispartofTurkish Journal of Surgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectChemical peeling
dc.subjectskin cancer
dc.subjecttrichloroaceticacid
dc.titleA new practice of trichloroaceticacid peeling: reduction of second primary skin cancer
dc.title.alternativeIkinci primer cilt kanserini önlemek için trikloroasetik asit ile peeling
dc.typeArticle

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