Association between polypharmacy and mortality in the community dwelling elderly: A retrospective cohort study

dc.authorid0000-0003-1520-8464
dc.authorid0000-0001-5037-7306
dc.authorid0000-0003-4197-1914
dc.contributor.authorKilincarslan, Mehmet Goktug
dc.contributor.authorCibik, Birol
dc.contributor.authorSahin, Erkan Melih
dc.date.accessioned2026-02-03T12:02:44Z
dc.date.available2026-02-03T12:02:44Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn this study, we examined the association between the use of multiple medications (polypharmacy) and mortality in 116 community-dwelling elderly people. This retrospective cohort study included 116 participants randomly selected from a population of 1161 community-dwelling elderly individuals. Of the 116 participants, 60 (51.72 %) were female, with a mean age of 74.09 6.53 years at the start of the study in 2015. After a median follow-up of 2932 days, 37 participants (31.90 %) were identified as deceased. The results showed that higher mortality was associated with increased medication adherence and a higher total number of medications. Notably, the use of topical medications did not contribute to the observed mortality. When assessing polypharmacy, it is recommended to exclude topical medications from the count, as they were found to have no effect on mortality. These findings highlight the need for thoughtful medication management to improve health outcomes in older populations. (c) 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
dc.identifier.doi10.1016/j.gerinurse.2025.103479
dc.identifier.issn0197-4572
dc.identifier.issn1528-3984
dc.identifier.pmid40845620
dc.identifier.scopus2-s2.0-105013799245
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.gerinurse.2025.103479
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34850
dc.identifier.volume65
dc.identifier.wosWOS:001592120300001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMosby-Elsevier
dc.relation.ispartofGeriatric Nursing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260130
dc.subjectPolypharmacy
dc.subjectMedication adherence
dc.subjectMortality determinants
dc.subjectTopical administration
dc.subjectRetrospective Study
dc.titleAssociation between polypharmacy and mortality in the community dwelling elderly: A retrospective cohort study
dc.typeArticle

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