Epicardial adipose tissue thickness in patients with ankylosing spondylitis

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dc.authoridates, can/0000-0003-2286-4398
dc.authoridArslan, Muhammet/0000-0001-5565-0770
dc.contributor.authorResorlu, Hatice
dc.contributor.authorAkbal, Ayla
dc.contributor.authorResorlu, Mustafa
dc.contributor.authorGokmen, Ferhat
dc.contributor.authorAtes, Can
dc.contributor.authorUysal, Fatma
dc.contributor.authorAdam, Gurhan
dc.date.accessioned2025-01-27T20:39:21Z
dc.date.available2025-01-27T20:39:21Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe purpose of our study was to measure epicardial adipose tissue (EAT) thickness as a novel indicator of atherosclerosis and cardiovascular risk factor in ankylosing spondylitis (AS) patients and to show the relationship with clinical parameters and inflammatory markers. Forty AS patients (42.75 +/- 12.43 years) and 40 healthy individuals with no cardiovascular risk factor as the control group (43.02 +/- 14.78 years) were included in the study. Carotid intima-media thickness (CIMT) and EAT thickness were measured in AS patients and the control group. Total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, glucose, erythrocyte sedimentation rate, urea, and blood pressure were investigated in both groups. In addition, the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) were used to evaluate the association between clinical findings and CIMT and EAT in the patient group. CIMT and EAT thickness were higher in the AS patients compared to the control group. CIMT was 0.76 +/- 0.19 and 0.57 +/- 0.12 mm (p < 0.001) and EAT thickness was 4.35 +/- 1.56 and 3.03 +/- 0.94 mm (p < 0.001) in the AS and control groups, respectively. A correlation was determined between EAT thickness and CIMT. Triglyceride level, patient age, blood pressure, and duration of disease were correlated with both CIMT and EAT thickness. Increased CIMT and EAT thickness in AS patients compared to the control group shows a risk for subclinical atherosclerosis and cardiovascular disease.
dc.identifier.doi10.1007/s10067-014-2568-4
dc.identifier.endpage299
dc.identifier.issn0770-3198
dc.identifier.issn1434-9949
dc.identifier.issue2
dc.identifier.pmid24647981
dc.identifier.scopus2-s2.0-84922970925
dc.identifier.scopusqualityQ1
dc.identifier.startpage295
dc.identifier.urihttps://doi.org/10.1007/s10067-014-2568-4
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23929
dc.identifier.volume34
dc.identifier.wosWOS:000348803000015
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer London Ltd
dc.relation.ispartofClinical Rheumatology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectAnkylosingspondylitis
dc.subjectAtherosclerosis
dc.subjectCarotid intima-media thickness
dc.subjectEpicardial adipose tissue
dc.titleEpicardial adipose tissue thickness in patients with ankylosing spondylitis
dc.typeArticle

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