Determination of Phytochemical and Antibacterial Properties of Momordica charantia Seed Extracts

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dc.contributor.authorAltun, Mehzat
dc.contributor.authorOrhan, Zerife
dc.date.accessioned2025-01-27T19:22:40Z
dc.date.available2025-01-27T19:22:40Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn recent years, it has been essential to discover safe and effective antibacterial drugs because of rising antibiotic-resistant bacteria. In traditional medicine, plant extracts including biological active components have been used for therapeutic purposes. We aimed to evaluate the antimicrobial properties of the aqueous seed extract of Momordica charantia (M. charantia) on 9 pathogenic bacteria. The antibacterial activity of the extract was assessed against strains using disc diffusion and broth microdilution tests. A total of 21 constituents were identified from M.charantia seeds. Alcohols, esters, aldehydes, monoterpenes, and monoterpenoids were found as the prevalent groups. The seed extract showed the greatest antimicrobial activity on Bacillus subtilis (B. subtilis) and Staphylococcus aureus (S. aureus) with an inhibition zone diameter (IZD) value of 15.75±0.50 mm and 15.25±0.957 mm, respectively. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) test results ranged from 12.5 to 100 (mg/mL). The seed extract of M.charantia could be used for the cure of bacterial infections as a new natural drug.
dc.identifier.doi10.18466/cbayarfbe.1292919
dc.identifier.endpage313
dc.identifier.issn1305-130X
dc.identifier.issn1305-1385
dc.identifier.issue4
dc.identifier.startpage309
dc.identifier.trdizinid1222969
dc.identifier.urihttps://doi.org/10.18466/cbayarfbe.1292919
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1222969
dc.identifier.urihttps://hdl.handle.net/20.500.12428/15175
dc.identifier.volume19
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofCelal Bayar Üniversitesi Fen Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectBiyoloji
dc.subjectMikrobiyoloji
dc.titleDetermination of Phytochemical and Antibacterial Properties of Momordica charantia Seed Extracts
dc.typeArticle

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