Sourdough microbiota in combination with bioengineering tools towards preparation of functional molecules from bovine colostrum for agri-food, nutraceutical, cosmetic and pharmaceutical industry

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dc.authoridKarav, Sercan / 0000-0003-4056-1673
dc.contributor.authorRocha, João Miguel
dc.contributor.authorKarav, Sercan
dc.contributor.authorBartkiene, Elena
dc.date.accessioned2025-01-27T19:04:29Z
dc.date.available2025-01-27T19:04:29Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description1st International on-line conference Lithuanian University of Health Sciences, Veterinary Academy, Department of Food Safety and Quality and Lithuanian Academy of Science 19 June 2024, Kaunas
dc.description.abstractBovine colostrum, also known as “first milk” or “first food”, is produced by healthy mammary glands until the first 72 hours post-partum, after which it acquires the typical physicochemical, microbiological, nutritional and rheological characteristics of milk. Colostrum is composed of unique bioactive compounds, which are divided into two main classes: immunological (immunoglobulins, antibodies, proline-rich polypeptides, glycomacropeptides, glycoproteins, lactalbumins, lactoferrin, lactoperoxidase, cytokines, lysozymes) and growth factors [epidermal (EgF), insulin like (IgF-1 and IgF-2), transforming (TgF-A and TgF-B) and plaquette-derived growth factors, vitamins and minerals]. The use of colostrum to treat illnesses and to contribute to the well-being dates from thousands of years ago. The prophylactic and therapeutical use of immune milk presented satisfactory success in the prevention and treatment of bacterial infections produced by Escherichia coli strains, in gastroenteritis treatments in children originated by rotavirus, in the treatment of cryptoccidiosis (or cryptococcal disease, a disease caused by one of two species of fungi belonging to the genus of Cryptococcus) and diarrhoea in patients with acquired immune deficiency syndrome (AIDS) and other immunological illnesses, and in the prevention of dental caries, among many other examples. In all these cases, colostrum was collected from cows previously hyper-immunised with specific pathogens. Thanks to the biotechnological advances obtained in the last decades, it has been demonstrated that the immunological and growth factors present in colostrum composition are transferable along all the food chain between mammal species and are not species-specific. Hence, a major opportunity to expand the renewed market niche of colostrum has emerged rapidly and its reintroduction in the market depends in biotechnological breakthroughs. In this context, this presentation is focused in research studies that have been undertaken aiming at the implementation of a novel biological technology for the production of functional molecules from bovine colostrum through bioengineering tools based on the ultrasonication in combination with sourdough LAB fermentation and dehydration, resulting in a safe material with constant quality and a very high-added value for the development of innovative products in the pharmaceutical, cosmetic, nutraceutical and agri-food industry. This new technological approach to process and use the bovine colostrum represents a breakthrough that worth exploring.
dc.identifier.endpage89
dc.identifier.issn1392-2130
dc.identifier.scopus2-s2.0-85212978738
dc.identifier.scopusqualityQ4
dc.identifier.startpage89
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13966
dc.identifier.volume82(1)
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherLietuvos Veterinarijos Akademija
dc.relation.ispartofVeterinarija ir Zootechnika
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectbioactive compounds
dc.subjectbovine colostrum
dc.subjectgrowth factors
dc.subjectimmunological compounds
dc.subjectlactic acids bacteria (LAB)
dc.subjectprophylactic
dc.subjecttherapeutic
dc.titleSourdough microbiota in combination with bioengineering tools towards preparation of functional molecules from bovine colostrum for agri-food, nutraceutical, cosmetic and pharmaceutical industry
dc.typeConference Object

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