The effect of anaesthesia technique on maternal and cord blood ischaemia-modified albumin levels during caesarean section: A randomized controlled study

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dc.authoridHanci, Volkan/0000-0002-2227-194X
dc.contributor.authorOmur, Dilek
dc.contributor.authorHacivelioglu, Servet Ozden
dc.contributor.authorOguzalp, Huseyin
dc.contributor.authorUyan, Berna
dc.contributor.authorKiraz, Hasan Ali
dc.contributor.authorDuman, Can
dc.contributor.authorTutunculer, Funda Kirtay
dc.date.accessioned2025-01-27T20:46:04Z
dc.date.available2025-01-27T20:46:04Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Ischaemia-modified albumin (IMA) is an early marker for various ischaemic events, including cardiac ischaemia. This study determined variations in IMA levels during caesarean section, performed under general anaesthesia or with combined spinal epidural anaesthesia. Methods: Full-term, healthy pregnant women were allocated to undergo caesarean section, using either general anaesthesia or combined spinal epidural anaesthesia. IMA and albumin levels were measured in maternal serum samples taken immediately prior to caesarean section and 30min into the procedure, as well as from serum taken from cord blood after double clamping. Results: At total of 51 healthy pregnant women underwent either general anaesthesia (n=28) or combined spinal epidural anaesthesia (n=23). Within-group analysis of the general anaesthesia group showed that both IMA levels and IMA/albumin ratios were significantly higher at 30min of surgery compared with the immediate preoperative period. Conclusions: Lower IMA levels in the combined spinal epidural anaesthesia group may have been due to improved balancing of oxidative stress during caesarean section. Further research on IMA levels during caesarean section should take into account the method of anaesthesia used.
dc.identifier.doi10.1177/0300060512474133
dc.identifier.endpage1119
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue4
dc.identifier.pmid23857160
dc.identifier.scopus2-s2.0-84887398821
dc.identifier.scopusqualityQ2
dc.identifier.startpage1111
dc.identifier.urihttps://doi.org/10.1177/0300060512474133
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24800
dc.identifier.volume41
dc.identifier.wosWOS:000322507100021
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltd
dc.relation.ispartofJournal of International Medical Research
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectAlbumin
dc.subjectcaesarean section
dc.subjectcombined spinal epidural anaesthesia
dc.subjectcord blood
dc.subjectgeneral anaesthesia
dc.subjectischaemia-modified albumin
dc.titleThe effect of anaesthesia technique on maternal and cord blood ischaemia-modified albumin levels during caesarean section: A randomized controlled study
dc.typeArticle

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