Scleroderma renal crisis and ovarian hyperstimulation syndrome related to the use of clomiphene in a patient with scleroderma

dc.authoridKOBAK, SENOL/0000-0001-8270-640X
dc.contributor.authorKobak, Senol
dc.contributor.authorHacivelioglu, Servet
dc.contributor.authorGungor, Selen
dc.date.accessioned2025-01-27T21:13:10Z
dc.date.available2025-01-27T21:13:10Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis paper presented a 28-year-old female with systemic sclerosis who developed scleroderma renal crisis and ovarian hyperstimulation syndrome following clomiphene administration. Urgent therapy including angiotensin-converting enzyme (ACE) inhibitors and supportive care resulted in regression and eventually resolution of all the clinical and laboratory symptoms. Although scleroderma renal crisis is a fatal complication of high-dose corticosteroids, rarely is this seen with the use of ACE inhibitors. This case report aimed to investigate the potential capacity of the selective oestrogen receptor modulator clomiphene to induce scleroderma renal crisis as well as corticosteroids. (C) 2012 Elsevier Espana, S.L. All rights reserved.
dc.identifier.doi10.1016/j.reuma.2012.11.003
dc.identifier.endpage53
dc.identifier.issn1699-258X
dc.identifier.issn1885-1398
dc.identifier.issue1
dc.identifier.pmid23623920
dc.identifier.scopus2-s2.0-84895071024
dc.identifier.scopusqualityQ3
dc.identifier.startpage51
dc.identifier.urihttps://doi.org/10.1016/j.reuma.2012.11.003
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28322
dc.identifier.volume10
dc.identifier.wosWOS:000421419100012
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Doyma Sl
dc.relation.ispartofReumatologia Clinica
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectScleroderma renal crisis
dc.subjectOvarian hyperstimulation syndrome
dc.subjectClomiphene
dc.titleScleroderma renal crisis and ovarian hyperstimulation syndrome related to the use of clomiphene in a patient with scleroderma
dc.typeArticle

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