Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications

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dc.authoridAkdasci, Emir/0009-0009-5996-6567
dc.authoridbechelany, mikhael/0000-0002-2913-2846
dc.authoridEker, Furkan/0009-0002-5260-6111
dc.contributor.authorAkdasci, Emir
dc.contributor.authorDuman, Hatice
dc.contributor.authorEker, Furkan
dc.contributor.authorBechelany, Mikhael
dc.contributor.authorKarav, Sercan
dc.date.accessioned2025-05-29T02:57:22Z
dc.date.available2025-05-29T02:57:22Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractChitosan, a multifaceted amino polysaccharide biopolymer derived from chitin, has extensive antibacterial efficacy against diverse pathogenic microorganisms, including both Gram-negative and Gram-positive bacteria, in addition to fungi. Over the course of the last several decades, chitosan nanoparticles (NPs), which are polymeric and bio-based, have garnered a great deal of interest as efficient antibacterial agents. This is mostly due to the fact that they are used in a wide variety of applications, including medical treatments, food, chemicals, and agricultural products. Within the context of the antibacterial mechanism of chitosan and chitosan NPs, we present a review that provides an overview of the synthesis methods, including novel procedures, and compiles the applications that have been developed in the field of biomedicine. These applications include wound healing, drug delivery, dental treatment, water purification, agriculture, and food preservation. In addition to this, we focus on the mechanisms of action and the factors that determine the antibacterial activity of chitosan and its derivatives. In conjunction with this line of inquiry, researchers are strongly urged to concentrate their efforts on developing novel and ground-breaking applications of chitosan NPs.
dc.identifier.doi10.3390/nano15020126
dc.identifier.issn2079-4991
dc.identifier.issue2
dc.identifier.pmid39852740
dc.identifier.scopus2-s2.0-85215824091
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/nano15020126
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30034
dc.identifier.volume15
dc.identifier.wosWOS:001404184900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofNanomaterials
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250529
dc.subjectchitosan
dc.subjectchitosan nanoparticles
dc.subjectantibacterial
dc.subjectdrug delivery
dc.subjectagriculture
dc.subjectnanocomposites
dc.subjectphysicochemical property
dc.subjectchitosan synthesis
dc.subjectfood preservation
dc.titleChitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications
dc.typeReview

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