Effects of acute twelve minute run test on oxidative stress and antioxidant enzyme activities

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dc.authoridSaritas, Nazmi/0000-0003-3402-6498
dc.contributor.authorSaritas, Nazmi
dc.contributor.authorUyanik, Fatma
dc.contributor.authorHamurcu, Zuhal
dc.contributor.authorCoksevim, Bekir
dc.date.accessioned2025-01-27T20:43:34Z
dc.date.available2025-01-27T20:43:34Z
dc.date.issued2011
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe aim of this study was to investigate the effects of 12 min run test on oxidative stress, some antioxidant enzyme activities, and muscle and DNA damage. Twenty two healthy and well trained male athletes were recruited to this study. The 12 min run test, cooper test, was applied to the participating athletes. The blood samples were taken before, immediately after and 24 h after the run test, and sera and plasma were separated and then stored at -80 degrees C until the analysis. Serum MDA and NO levels as the indicators of oxidative damage; serum SOD and CAT, plasma GPx activities as the indicators of antioxidant defense system; serum 8-OHdG as the indicator of DNA damage, CK and LHD enzyme activities as the indicators of muscle damage, and glucose level were measured. Serum SOD, NO, CAT, and 8-OHdG levels showed no significant changes before, immediately after and 24 h after the run rest. There was a significant decrease in serum MDA level immediately after exercise, which is returned to baseline level after 24 h-rest period (p<0.05). Serum LHD (p<0.001) and CK activities (p<0.05) and glucose level (p<0.001) increased immediately after exercise but these increments returned to pre-exercise level after 24 h-rest period. Acute twelve minute endurance exercise increased CK, LDH and glucose decreased oxidative stress and whereas has no effect on antioxidant capacity and DNA damage in trained young men.
dc.description.sponsorshipErciyes University, Research Foundation [BSYO-07-01]
dc.description.sponsorshipErciyes University, Research Foundation has supported this research (contract grant number BSYO-07-01).
dc.identifier.doi10.5897/AJPP11.263
dc.identifier.endpage1222
dc.identifier.issn1996-0816
dc.identifier.issue9
dc.identifier.scopus2-s2.0-80052883884
dc.identifier.scopusqualityN/A
dc.identifier.startpage1218
dc.identifier.urihttps://doi.org/10.5897/AJPP11.263
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24272
dc.identifier.volume5
dc.identifier.wosWOS:000295802000005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAcademic Journals
dc.relation.ispartofAfrican Journal of Pharmacy and Pharmacology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAntioxidant enzymes
dc.subjectexercise
dc.subjectoxidative stress
dc.subjecttwelve minute run test
dc.titleEffects of acute twelve minute run test on oxidative stress and antioxidant enzyme activities
dc.typeArticle

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