Assessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjects

Basit Öğe Kaydı
dc.authoridDemiroz Tasolar, Sevgi/0000-0002-9836-6814
dc.contributor.authorTasolar, Hakan
dc.contributor.authorMete, Turkan
dc.contributor.authorBalli, Mehmet
dc.contributor.authorAltun, Burak
dc.contributor.authorCetin, Mustafa
dc.contributor.authorYuce, Tuncay
dc.contributor.authorTasolar, Sevgi
dc.date.accessioned2025-01-27T21:02:05Z
dc.date.available2025-01-27T21:02:05Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAimEven though polycystic ovary syndrome (PCOS) is characterized by increased inflammatory activity and insulin resistance, there is no clinical data about whether risk of atrial fibrillation are increased in these patients. We aimed to evaluate atrial conduction parameters predicting atrial involvement in this patient group. MethodsThe study population comprised 50 women 18-40 years of age who had been diagnosed with PCOS. The patients were divided into two groups: lean women (L-PCOS) with a body mass index (BMI) under 25kg/m(2) and obese women (O-PCOS) with a BMI greater than 30kg/m(2). Twenty-five age-matched lean healthy women were enrolled voluntarily as the control group. Difference between maximum and minimum P-wave duration was calculated and was defined as P-wave dispersion (Pd). Inter- and intra-atrial electromechanical delays (inter-AED, intra-AED, respectively) were measured with tissue Doppler imaging. ResultsInter- and intra-AED parameters were higher in the L-PCOS group when compared with control subjects (anova, P=0.004 and P=0.013, respectively), and were also significantly higher in the O-PCOS group compared with other groups (anova, P<0.001 for both). The regression analyses indicated that Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR) (=0.603, P<0.001) and BMI (=0.379, P<0.001) were the independent predictors of inter-AED, HOMA-IR (=0.835, P<0.001) was an independent predictor of intra-AED, and BMI (=0.457, P=0.006) and the left atrial diameter (=0.350, P<0.034) were independent predictors of Pd. ConclusionConsequently, our findings provide data regarding prolonged atrial conduction parameters in PCOS patients, especially when accompanied by obesity.
dc.identifier.doi10.1111/jog.12308
dc.identifier.endpage1066
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue4
dc.identifier.pmid24612019
dc.identifier.scopus2-s2.0-84903554672
dc.identifier.scopusqualityQ2
dc.identifier.startpage1059
dc.identifier.urihttps://doi.org/10.1111/jog.12308
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27277
dc.identifier.volume40
dc.identifier.wosWOS:000333615200023
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Obstetrics and Gynaecology Research
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectatrial electromechanical delay
dc.subjectatrial fibrillation
dc.subjectinsulin resistance
dc.subjectleft ventricular diastolic dysfunction
dc.subjectobesity
dc.subjectpolycystic ovary syndrome
dc.titleAssessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjects
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu